A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery

Acanthamoeba are ubiquitous microorganisms and are considered opportunistic pathogens in humans. Acanthamoeba infection involving the vitreous, retina or choroid is uncommon and is mostly seen following corneal infections or corneal transplant surgeries. (1,2) We present a rare case of post-operativ...

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Main Authors: Vishal Raval, Rushil Saxena, Joveeta Joseph, Savitri Sharma, Raja Narayanan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-04-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.670
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author Vishal Raval
Rushil Saxena
Joveeta Joseph
Savitri Sharma
Raja Narayanan
author_facet Vishal Raval
Rushil Saxena
Joveeta Joseph
Savitri Sharma
Raja Narayanan
author_sort Vishal Raval
collection DOAJ
description Acanthamoeba are ubiquitous microorganisms and are considered opportunistic pathogens in humans. Acanthamoeba infection involving the vitreous, retina or choroid is uncommon and is mostly seen following corneal infections or corneal transplant surgeries. (1,2) We present a rare case of post-operative endophthalmitis due to Acanthamoeba in a 30-year old gentleman who underwent cataract surgery in his left eye. The initial routine microscopy and culture reports were negative for bacteria and fungus, and inspite of empirical treatment for endophthamitis, the patient's ocular condition worsened. Following multiple vitrectomy surgery and repeated negative culture as well as polymerase chain reaction (PCR) for bacteria, virus and fungi, PCR for Acanthamoeba species was reported positive. On starting the patient on intravitreal and topical voriconazole along with oral ketoconazole the patient's eye condition improved with moderate recovery of visual acuity. To the best of our knowledge, this is the first case reported of Acanthamoeba endophthalmitis following cataract surgery.
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publishDate 2021-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Delhi Journal of Ophthalmology
spelling doaj-art-816f06cd240744b2aaab30a7f6eb0cec2025-08-20T02:11:14ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842021-04-0131410310510.7869/djo.670A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract SurgeryVishal RavalRushil SaxenaJoveeta JosephSavitri SharmaRaja NarayananAcanthamoeba are ubiquitous microorganisms and are considered opportunistic pathogens in humans. Acanthamoeba infection involving the vitreous, retina or choroid is uncommon and is mostly seen following corneal infections or corneal transplant surgeries. (1,2) We present a rare case of post-operative endophthalmitis due to Acanthamoeba in a 30-year old gentleman who underwent cataract surgery in his left eye. The initial routine microscopy and culture reports were negative for bacteria and fungus, and inspite of empirical treatment for endophthamitis, the patient's ocular condition worsened. Following multiple vitrectomy surgery and repeated negative culture as well as polymerase chain reaction (PCR) for bacteria, virus and fungi, PCR for Acanthamoeba species was reported positive. On starting the patient on intravitreal and topical voriconazole along with oral ketoconazole the patient's eye condition improved with moderate recovery of visual acuity. To the best of our knowledge, this is the first case reported of Acanthamoeba endophthalmitis following cataract surgery.https://journals.lww.com/10.7869/djo.670acanthamoebapost cataract surgery endophthalmitispars plana vitrectomy
spellingShingle Vishal Raval
Rushil Saxena
Joveeta Joseph
Savitri Sharma
Raja Narayanan
A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
Delhi Journal of Ophthalmology
acanthamoeba
post cataract surgery endophthalmitis
pars plana vitrectomy
title A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
title_full A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
title_fullStr A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
title_full_unstemmed A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
title_short A Rare Case Of Acanthamoeba Endophthalmitis Following Cataract Surgery
title_sort rare case of acanthamoeba endophthalmitis following cataract surgery
topic acanthamoeba
post cataract surgery endophthalmitis
pars plana vitrectomy
url https://journals.lww.com/10.7869/djo.670
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