Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests

Background. The aim of this study was to monitor the cases identified as hepatitis B carriers during premarital tests, to vaccinate their prospective spouses with a rapid vaccination scheme, and to compare the anti-HBs responses with the traditional vaccination scheme. Methods. Blood samples of 1250...

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Main Authors: Selma Tosun, Murat Yücetürk, Aydın Bilal Dönmez, Turan Gündüz
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/843134
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author Selma Tosun
Murat Yücetürk
Aydın Bilal Dönmez
Turan Gündüz
author_facet Selma Tosun
Murat Yücetürk
Aydın Bilal Dönmez
Turan Gündüz
author_sort Selma Tosun
collection DOAJ
description Background. The aim of this study was to monitor the cases identified as hepatitis B carriers during premarital tests, to vaccinate their prospective spouses with a rapid vaccination scheme, and to compare the anti-HBs responses with the traditional vaccination scheme. Methods. Blood samples of 1250 couple spouses were tested for HBsAg and anti-HBs. HBsAg positive cases' fiancées which were found HBV negative were administered a rapid three-dose vaccination scheme on days 0, 7, and 21. Forty controls with similar age and gender were also were administered three doses of the same vaccine. Results. Out of 1250 cases (625 couples), 46 (3.6%) were HBsAg positive, and 40 of them aged between 18 and 39 were admitted to the rapid vaccination program. Conclusion. Upon determination of HBsAg positivity in premarital tests, a rapid vaccination program provides early protection, but the 6th and 12th month vaccinations are also required. Anti-HBs response should be monitored.
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id doaj-art-8160f35f51fe41ab87aabdc66fac2321
institution Kabale University
issn 1740-2522
1740-2530
language English
publishDate 2012-01-01
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series Clinical and Developmental Immunology
spelling doaj-art-8160f35f51fe41ab87aabdc66fac23212025-08-20T03:35:06ZengWileyClinical and Developmental Immunology1740-25221740-25302012-01-01201210.1155/2012/843134843134Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital TestsSelma Tosun0Murat Yücetürk1Aydın Bilal Dönmez2Turan Gündüz3Department of Clinical Microbiology and Infectious Diseases, Manisa State Hospital, Manisa, TurkeyPrimary Health Care Clinic No. 2, Turgutlu, Manisa, TurkeyPrimary Health Care Clinic No. 2, Turgutlu, Manisa, TurkeyDepartment of Microbiology, Vocational School of Health Services, Celal Bayar University, Manisa, TurkeyBackground. The aim of this study was to monitor the cases identified as hepatitis B carriers during premarital tests, to vaccinate their prospective spouses with a rapid vaccination scheme, and to compare the anti-HBs responses with the traditional vaccination scheme. Methods. Blood samples of 1250 couple spouses were tested for HBsAg and anti-HBs. HBsAg positive cases' fiancées which were found HBV negative were administered a rapid three-dose vaccination scheme on days 0, 7, and 21. Forty controls with similar age and gender were also were administered three doses of the same vaccine. Results. Out of 1250 cases (625 couples), 46 (3.6%) were HBsAg positive, and 40 of them aged between 18 and 39 were admitted to the rapid vaccination program. Conclusion. Upon determination of HBsAg positivity in premarital tests, a rapid vaccination program provides early protection, but the 6th and 12th month vaccinations are also required. Anti-HBs response should be monitored.http://dx.doi.org/10.1155/2012/843134
spellingShingle Selma Tosun
Murat Yücetürk
Aydın Bilal Dönmez
Turan Gündüz
Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
Clinical and Developmental Immunology
title Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
title_full Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
title_fullStr Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
title_full_unstemmed Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
title_short Rapid Immunization Scheme for Spouses of Individuals Estabilished as Hepatitis B Carriers during Premarital Tests
title_sort rapid immunization scheme for spouses of individuals estabilished as hepatitis b carriers during premarital tests
url http://dx.doi.org/10.1155/2012/843134
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