Reproductive disorders in the experimental modeling of tuberculosis
For experimental modeling of tuberculosis, animals of various species are used, each of which has its own advantages and disadvantages. Specific characteristics of animal genetics and immunology during the development of tuberculosis in the experiment were studied in sufficient detail. In addition,...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
New Terra Publishing House
2020-03-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1400 |
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| _version_ | 1850223886833025024 |
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| author | S. I. Kayukova N. V. Sterzhanova B. V. Nikonenko |
| author_facet | S. I. Kayukova N. V. Sterzhanova B. V. Nikonenko |
| author_sort | S. I. Kayukova |
| collection | DOAJ |
| description | For experimental modeling of tuberculosis, animals of various species are used, each of which has its own advantages and disadvantages. Specific characteristics of animal genetics and immunology during the development of tuberculosis in the experiment were studied in sufficient detail. In addition, mice, guinea pigs, and primates are widely used to test new vaccines and candidate drugs. Modeling of tuberculosis of reproductive organs of females has been developed much worse, since artificial approaches to reproducing genital tuberculosis which do not correspond to the real development of pathology in humans, are more often used. The review describes aspects of modeling tuberculosis as systemic and local infectious process including the study of disorders in the reproductive system of female animals during the development of pulmonary tuberculosis. |
| format | Article |
| id | doaj-art-814f06d054d54d989d3b288adffc646e |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2020-03-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-814f06d054d54d989d3b288adffc646e2025-08-20T02:05:48ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062020-03-01982525610.21292/2075-1230-2020-98-2-52-561400Reproductive disorders in the experimental modeling of tuberculosisS. I. Kayukova0N. V. Sterzhanova1B. V. Nikonenko2Central Tuberculosis Research InstituteCentral Tuberculosis Research InstituteCentral Tuberculosis Research InstituteFor experimental modeling of tuberculosis, animals of various species are used, each of which has its own advantages and disadvantages. Specific characteristics of animal genetics and immunology during the development of tuberculosis in the experiment were studied in sufficient detail. In addition, mice, guinea pigs, and primates are widely used to test new vaccines and candidate drugs. Modeling of tuberculosis of reproductive organs of females has been developed much worse, since artificial approaches to reproducing genital tuberculosis which do not correspond to the real development of pathology in humans, are more often used. The review describes aspects of modeling tuberculosis as systemic and local infectious process including the study of disorders in the reproductive system of female animals during the development of pulmonary tuberculosis.https://www.tibl-journal.com/jour/article/view/1400m. tuberculosistuberculosisexperimental animalsinflammationmicrobiome |
| spellingShingle | S. I. Kayukova N. V. Sterzhanova B. V. Nikonenko Reproductive disorders in the experimental modeling of tuberculosis Туберкулез и болезни лёгких m. tuberculosis tuberculosis experimental animals inflammation microbiome |
| title | Reproductive disorders in the experimental modeling of tuberculosis |
| title_full | Reproductive disorders in the experimental modeling of tuberculosis |
| title_fullStr | Reproductive disorders in the experimental modeling of tuberculosis |
| title_full_unstemmed | Reproductive disorders in the experimental modeling of tuberculosis |
| title_short | Reproductive disorders in the experimental modeling of tuberculosis |
| title_sort | reproductive disorders in the experimental modeling of tuberculosis |
| topic | m. tuberculosis tuberculosis experimental animals inflammation microbiome |
| url | https://www.tibl-journal.com/jour/article/view/1400 |
| work_keys_str_mv | AT sikayukova reproductivedisordersintheexperimentalmodelingoftuberculosis AT nvsterzhanova reproductivedisordersintheexperimentalmodelingoftuberculosis AT bvnikonenko reproductivedisordersintheexperimentalmodelingoftuberculosis |