In-depth analysis of the mode of action of resveratrol: genome-wide characterization of G-quadruplex binding properties

In-depth analysis of the mode of action of resveratrol: genome-wide characterization of G-quadruplex binding properties

Abstract Background Resveratrol (RSV) is one of the most studied and used biomolecules, for which many pharmacological effects targeting multiple tissues have been described. However, a common underlying mechanism driving its full pharmacological activity has not been described in detail. G-quadrupl...

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Main Authors: Ana Soriano-Lerma, Victoria Sánchez-Martín, Javier Murciano-Calles, Matilde Ortiz-González, María J. Tello-López, Virginia Pérez-Carrasco, Ángel Linde-Rodríguez, Inmaculada Ramírez-Macías, Irene Gómez-Pìnto, Inmaculada López-Aliaga, Miguel Soriano, Jose A. Garcia Salcedo
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cellular & Molecular Biology Letters
Subjects:
Small molecule
DNA binding
G-quadruplex
Resveratrol
Secondary DNA structures
Online Access:https://doi.org/10.1186/s11658-025-00747-1
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