Optimizing the thermostability of triketone dioxygenase for engineering tolerance to mesotrione herbicide in soybean and cotton

Optimizing the thermostability of triketone dioxygenase for engineering tolerance to mesotrione herbicide in soybean and cotton

Optimized triketone dioxygenase (TDO) variants with enhanced temperature stability parameters were engineered to enable robust triketone tolerance in transgenic cotton and soybean crops. This herbicide tolerance trait, which can metabolize triketone herbicides such as mesotrione and tembotrione, cou...

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Bibliographic Details
Main Authors: Stephen M. G. Duff, Lei Shi, Danqi Chen, Xiaoran Fu, Mingsheng Peng, Clayton T. Larue, Janice Weihe, Jessica Koczan, Brian Krebel, Qungang Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Plant Science
Subjects:
protein engineering
triketone dioxygenase
4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors
protein variants
weed management
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2024.1502454/full
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