Network Pharmacology and Serum Nontargeted Metabolomics Reveal the Protective Effects of Propionate Against Liver Damage Induced by a High-Fat and AGE-Rich Diet in Diabetic Mice

Network Pharmacology and Serum Nontargeted Metabolomics Reveal the Protective Effects of Propionate Against Liver Damage Induced by a High-Fat and AGE-Rich Diet in Diabetic Mice

Diabetic liver injury is a leading cause of mortality in diabetes, with no specific treatment available. Sodium propionate (NaP) has anti-inflammatory and antioxidant properties, but its effectiveness in treating diabetic liver injury is still lacking research. The study employed network pharmacolog...

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Bibliographic Details
Main Authors: Liang Wu, Jiajun Tan, Wen Sun, Xueyun Dong, Jiayuan He, Asmaa Ali, Min Chen, Leilei Zhang, Pingping Wang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/jdr/3955893
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