Predictive Significance of Combined Plasmatic Detection of BRAF Mutations and S100B Tumor Marker in Early‐Stage Malignant Melanoma

Predictive Significance of Combined Plasmatic Detection of BRAF Mutations and S100B Tumor Marker in Early‐Stage Malignant Melanoma

ABSTRACT Background Melanoma is the most aggressive skin cancer with ability to recur also after early‐stage tumor surgery. The aim was to identify early‐stage melanoma patients at high risk of recurrence using liquid biopsy, estimating of mutated BRAF ctDNA and the level of tumor marker S100B in pl...

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Main Authors: Jiri Polivka, Mohamed A. Gouda, Mahyar Sharif, Martin Pesta, Helen Huang, Inka Treskova, Vlastimil Woznica, Jindra Windrichova, Katerina Houfkova, Radek Kucera, Tomas Fikrle, Jan Ricar, Kristyna Pivovarcikova, Ondrej Topolcan, Filip Janku
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Cancer Medicine
Subjects:
BRAF V600E
ctDNA
ddPCR
melanoma
S100B
Online Access:https://doi.org/10.1002/cam4.70313
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