RNA-binding protein HuR inhibition induces multiple programmed cell death in breast and prostate cancer

RNA-binding protein HuR inhibition induces multiple programmed cell death in breast and prostate cancer

Abstract The RNA-binding protein Hu antigen R (HuR) plays a pivotal role in cancer progression, and previous studies have demonstrated its involvement in suppressing cell death in cancer. However, the precise mechanisms underlying HuR inhibition-induced cell death remain elusive. Here, we investigat...

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Bibliographic Details
Main Authors: Lanjing Wei, Sung Hae Kim, Ahlam M. Armaly, Jeffrey Aubé, Liang Xu, Xiaoqing Wu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
HuR
Cell death
Breast cancer
Prostate cancer
Mouse tumor models
Online Access:https://doi.org/10.1186/s12964-024-01916-z
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