Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer

Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer

Abstract Background Tertiary lymphoid structures (TLS) correlate with tumour prognosis and immunotherapy responses in gastric cancer (GC) studies. However, understanding the complex and diverse immune microenvironment within TLS requires comprehensive analysis. Methods We examined the prognostic imp...

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Bibliographic Details
Main Authors: Yi Xie, Haoxin Peng, Yajie Hu, Keren Jia, Jiajia Yuan, Dan Liu, Yanyan Li, Xujiao Feng, Jian Li, Xiaotian Zhang, Yu Sun, Lin Shen, Yang Chen
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Medicine
Subjects:
Gastric cancer
Tertiary lymphoid structures
Tumour microenvironment
Immunotherapy
Prognostic model
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s12916-025-03889-3
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https://doi.org/10.1186/s12916-025-03889-3

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