Genomic insights about the effect of sodium-glucose cotransporter 2 inhibitors: a systematic review

Genomic insights about the effect of sodium-glucose cotransporter 2 inhibitors: a systematic review

IntroductionHeart failure (HF) is a complex clinical syndrome with high morbidity and mortality, significantly burdening healthcare systems worldwide. Despite advances in therapy, effective treatment options remain limited. Sodium-glucose cotransporter 2 (SGLT2) inhibitors, initially developed for d...

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Main Authors: Pavitraa Saravana Kumar, Yogapriya Chidambaram, G. Shree Devi, Vettriselvi Venkatesan, Ramesh Sankaran, Nagendra Boopathy Senguttuvan, Thanikachalam Sadagopan, Dorairaj Prabhakaran
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Genetics
Subjects:
sodium-glucose cotransporter 2 inhibitors
heart failure
genomics
gene expression
inflammatory biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1571032/full
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