Design of a multi-epitope vaccine candidate against Helicobacter pylori in gastric cancer: an immunoinformatic approach

Design of a multi-epitope vaccine candidate against Helicobacter pylori in gastric cancer: an immunoinformatic approach

Background: Gastric cancer and peptic ulcers can both be caused by Helicobacter pylori (H. pylori). The complexity of such a bacterium has made it difficult to develop an effective treatment. Thus, a computational approach to developing antigenicity, stability, and safety in vaccines against this pa...

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Bibliographic Details
Main Authors: Shojaeian, Ali, Sanami, Samira, Mahmoudvand, Shahab, Amini, Razieh, Alibakhshi, Abbas
Format: Article
Language:deu
Published: German Medical Science GMS Publishing House 2025-06-01
Series:GMS Hygiene and Infection Control
Subjects:
helicobacter pylori
multi-epitope vaccine
gastric cancer
molecular docking
molecular dynamics
saba
baba
Online Access:https://journals.publisso.de/en/journals/hic/volume20/dgkh000556
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