Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report
A 3-year-old, 10.2 kg, spayed, female mixed-breed dog was diagnosed with systemic lupus erythematosus. The patient was administered intravenous methylprednisolone at a dose of 2 mg/kg twice daily. Over the next 24 h, the dog’s heart rate dropped to 42–48 bpm, while other vital signs remained stable....
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MDPI AG
2025-01-01
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| author | Fang-Chi Tsou Eng-Wen Lim Pin-Guang Jann Pin-Chen Liu |
| author_facet | Fang-Chi Tsou Eng-Wen Lim Pin-Guang Jann Pin-Chen Liu |
| author_sort | Fang-Chi Tsou |
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| description | A 3-year-old, 10.2 kg, spayed, female mixed-breed dog was diagnosed with systemic lupus erythematosus. The patient was administered intravenous methylprednisolone at a dose of 2 mg/kg twice daily. Over the next 24 h, the dog’s heart rate dropped to 42–48 bpm, while other vital signs remained stable. A 12-lead electrocardiogram revealed sinus bradycardia without any other arrhythmia. Notably, the dog was not receiving any beta-blockers or undergoing other therapies commonly associated with sinus bradycardia. After tapering the corticosteroid dose, no further episodes of bradycardia were observed. Herein, we report the first case of sinus bradycardia in a dog following intravenous methylprednisolone therapy to improve veterinarians’ understanding of corticosteroid-induced cardiac arrhythmias. |
| format | Article |
| id | doaj-art-811fe0b4cb22423fa98e4fabb02de4f6 |
| institution | DOAJ |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
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| series | Animals |
| spelling | doaj-art-811fe0b4cb22423fa98e4fabb02de4f62025-08-20T02:48:01ZengMDPI AGAnimals2076-26152025-01-0115337510.3390/ani15030375Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case ReportFang-Chi Tsou0Eng-Wen Lim1Pin-Guang Jann2Pin-Chen Liu3Veterinary Medical Teaching Hospital, College of Veterinary Medicine, National Chung Hsing University, Taichung 402, TaiwanDepartment of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung 402, TaiwanDepartment of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung 402, TaiwanVeterinary Medical Teaching Hospital, College of Veterinary Medicine, National Chung Hsing University, Taichung 402, TaiwanA 3-year-old, 10.2 kg, spayed, female mixed-breed dog was diagnosed with systemic lupus erythematosus. The patient was administered intravenous methylprednisolone at a dose of 2 mg/kg twice daily. Over the next 24 h, the dog’s heart rate dropped to 42–48 bpm, while other vital signs remained stable. A 12-lead electrocardiogram revealed sinus bradycardia without any other arrhythmia. Notably, the dog was not receiving any beta-blockers or undergoing other therapies commonly associated with sinus bradycardia. After tapering the corticosteroid dose, no further episodes of bradycardia were observed. Herein, we report the first case of sinus bradycardia in a dog following intravenous methylprednisolone therapy to improve veterinarians’ understanding of corticosteroid-induced cardiac arrhythmias.https://www.mdpi.com/2076-2615/15/3/375high-dose corticosteroidmethylprednisolonesinus bradycardiasystemic lupus erythematosusdog |
| spellingShingle | Fang-Chi Tsou Eng-Wen Lim Pin-Guang Jann Pin-Chen Liu Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report Animals high-dose corticosteroid methylprednisolone sinus bradycardia systemic lupus erythematosus dog |
| title | Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report |
| title_full | Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report |
| title_fullStr | Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report |
| title_full_unstemmed | Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report |
| title_short | Corticosteroid-Induced Sinus Bradycardia in a Dog with Systemic Lupus Erythematosus: A Case Report |
| title_sort | corticosteroid induced sinus bradycardia in a dog with systemic lupus erythematosus a case report |
| topic | high-dose corticosteroid methylprednisolone sinus bradycardia systemic lupus erythematosus dog |
| url | https://www.mdpi.com/2076-2615/15/3/375 |
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