Functional exhaustion of CD4<sup>+</sup>T cells in HIV/HCV coinfected HAART-treated patients

Functional exhaustion of CD4<sup>+</sup>T cells in HIV/HCV coinfected HAART-treated patients

Infection with hepatitis C virus (HCV) is common among HIV-positive patients, with up to 50% of them being coinfected in Russia. While highly active antiretroviral therapy (HAART) suppresses HIV replication and restores the immune system of HIV-infected subjects, HCV coinfection interferes with CD4+...

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Bibliographic Details
Main Authors: V. V. Vlasova, L. B. Korolevskaya, O. A. Loginova, N. G. Shmagel, E. V. Saidakova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2023-06-01
Series:Медицинская иммунология
Subjects:
hiv-infection
hepatitis c
cd4+t cells
immune activation
immune exhaustion
cytokine production
Online Access:https://www.mimmun.ru/mimmun/article/view/2734
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