Longitudinal single cell profiling of epitope specific memory CD4+ T cell responses to recombinant zoster vaccine
Abstract Vaccination leads to rapid expansion of antigen-specific T cells within in the first few days. However, understanding of transcriptomic changes and fates of antigen-specific T cells upon vaccination remains limited. Here, we investigate the fate of memory CD4+ T cells upon reactivation to r...
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| Main Authors: | Xiaomin Wen, Alex K. Hu, Scott R. Presnell, Emily S. Ford, David M. Koelle, William W. Kwok |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57562-7 |
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