Bispecific antibody suppresses osteosarcoma aggressiveness through regulation of NF-κB signaling pathway

Osteosarcoma is one of the most lethal malignancies, and the prognosis remains dismal due to the paucity of effective therapeutic targets. Bmi-1 and TRIM-14 are associated with the initiation and progression of osteosarcoma, which could promote angiogenesis, invasion, and apoptotic resistance in bon...

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Bibliographic Details
Main Authors: Gui-Hua Yu, Ai-Min Li, Xiang Li, Zhong Yang, Hao Peng
Format: Article
Language:English
Published: SAGE Publishing 2017-06-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705572
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