Molecular alteration patterns predict tumor behavior in papillary thyroid carcinoma independent of tumor size: insights from an international multicenter retrospective study

Molecular alteration patterns predict tumor behavior in papillary thyroid carcinoma independent of tumor size: insights from an international multicenter retrospective study

Abstract Background Molecular testing is a well-established tool that assists in the management of thyroid nodules and allows classification in distinct molecular alteration patterns: BRAF-like, RAS-like and non-BRAF-non-RAS (NBNR). Yet classical TNM classification and ATA guidelines currently rely...

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Bibliographic Details
Main Authors: Grégoire B. Morand, Idit Tessler, Simon E. Thurnheer, Kayla E. Payne, Maxine Noik, Josh Krasner, Tzahi Yamin, Marc P. Pusztaszeri, Richard J. Payne, Galit Avior
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Thyroid Research
Subjects:
Thyroid Nodule
Thyroid Neoplasms
Molecular alteration
Radiation Exposure
Online Access:https://doi.org/10.1186/s13044-025-00231-0
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