Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept
Primary Sjögren’s syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s synd...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551094/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850211284207796224 |
|---|---|
| author | Juan Chen Fangfang Zhou Jian Shen Jun Pang Hanqing Chu |
| author_facet | Juan Chen Fangfang Zhou Jian Shen Jun Pang Hanqing Chu |
| author_sort | Juan Chen |
| collection | DOAJ |
| description | Primary Sjögren’s syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment. |
| format | Article |
| id | doaj-art-80ea635b9a0749698cd6b3c2203fcb42 |
| institution | OA Journals |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-80ea635b9a0749698cd6b3c2203fcb422025-08-20T02:09:35ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-04-011610.3389/fimmu.2025.15510941551094Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitaciceptJuan Chen0Fangfang Zhou1Jian Shen2Jun Pang3Hanqing Chu4Department of Nephrology, The Affiliated YangMing Hospital of NingBo University (Yuyao People’s Hospital), Ningbo, Zhejiang, ChinaDepartment of Nephrology, Ningbo No.2 Hospital, Ningbo, Zhejiang, ChinaDepartment of Nephrology, The Affiliated YangMing Hospital of NingBo University (Yuyao People’s Hospital), Ningbo, Zhejiang, ChinaDepartment of Nephrology, The Affiliated YangMing Hospital of NingBo University (Yuyao People’s Hospital), Ningbo, Zhejiang, ChinaDepartment of Nephrology, The Affiliated YangMing Hospital of NingBo University (Yuyao People’s Hospital), Ningbo, Zhejiang, ChinaPrimary Sjögren’s syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551094/fullprimary Sjögren’s syndromemembranous nephropathyTelitaciceptB cellsurine proteinalbumin |
| spellingShingle | Juan Chen Fangfang Zhou Jian Shen Jun Pang Hanqing Chu Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept Frontiers in Immunology primary Sjögren’s syndrome membranous nephropathy Telitacicept B cells urine protein albumin |
| title | Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept |
| title_full | Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept |
| title_fullStr | Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept |
| title_full_unstemmed | Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept |
| title_short | Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept |
| title_sort | case report a case of membranous nephropathy associated with primary sjogren s syndrome treated with telitacicept |
| topic | primary Sjögren’s syndrome membranous nephropathy Telitacicept B cells urine protein albumin |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551094/full |
| work_keys_str_mv | AT juanchen casereportacaseofmembranousnephropathyassociatedwithprimarysjogrenssyndrometreatedwithtelitacicept AT fangfangzhou casereportacaseofmembranousnephropathyassociatedwithprimarysjogrenssyndrometreatedwithtelitacicept AT jianshen casereportacaseofmembranousnephropathyassociatedwithprimarysjogrenssyndrometreatedwithtelitacicept AT junpang casereportacaseofmembranousnephropathyassociatedwithprimarysjogrenssyndrometreatedwithtelitacicept AT hanqingchu casereportacaseofmembranousnephropathyassociatedwithprimarysjogrenssyndrometreatedwithtelitacicept |