Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness.

Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness.

Human aging is associated with a progressive loss of muscle mass and strength and a concomitant fat accumulation in form of inter-muscular adipose tissue, causing skeletal muscle function decline and immobilization. Fat accumulation can also occur as intra-muscular triglycerides (IMTG) deposition in...

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Main Authors: Maria Conte, Francesco Vasuri, Giovanni Trisolino, Elena Bellavista, Aurelia Santoro, Alessio Degiovanni, Ermanno Martucci, Antonia D'Errico-Grigioni, Daniela Caporossi, Miriam Capri, Andrea B Maier, Olivier Seynnes, Laura Barberi, Antonio Musarò, Marco V Narici, Claudio Franceschi, Stefano Salvioli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0073709
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