The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review
Gliomas are the most prevalent primary tumors of the brain and spinal cord. Regrettably, the prognosis, especially for high-grade gliomas, remains quite bleak. In recent decades, there's been a growing trend to replace or combine radiotherapy with chemotherapy, targeted therapy, and personalize...
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| Format: | Article |
| Language: | English |
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Zabansaraye Parsian Novin Mehr Institute
2024-12-01
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| Series: | Journal of Current Oncology and Medical Sciences |
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| Online Access: | https://submission.journalofcoms.com/index.php/JCOMS/article/view/248 |
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| author | Arman Hamzei Sara Hallaji Seyed Farzin Hosseini Arman Keymoradzadeh |
| author_facet | Arman Hamzei Sara Hallaji Seyed Farzin Hosseini Arman Keymoradzadeh |
| author_sort | Arman Hamzei |
| collection | DOAJ |
| description | Gliomas are the most prevalent primary tumors of the brain and spinal cord. Regrettably, the prognosis, especially for high-grade gliomas, remains quite bleak. In recent decades, there's been a growing trend to replace or combine radiotherapy with chemotherapy, targeted therapy, and personalized treatment for different patients. For example, carboplatin and vincristine are considered standard treatments for some patients with unresectable pediatric low-grade gliomas. In recent years, ketogenic diet (KD) has emerged as a promising investigational therapy for CNS tumors, with researchers exploring its use in conjunction with existing treatment modalities. This review article delves into the mechanisms underlying KD's potential therapeutic effects on glioma and its efficacy, safety profile, and overall role in glioma treatment. |
| format | Article |
| id | doaj-art-80e1a006c13249bea15c5921db78da8e |
| institution | Kabale University |
| issn | 2783-3127 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Zabansaraye Parsian Novin Mehr Institute |
| record_format | Article |
| series | Journal of Current Oncology and Medical Sciences |
| spelling | doaj-art-80e1a006c13249bea15c5921db78da8e2025-01-15T06:46:06ZengZabansaraye Parsian Novin Mehr InstituteJournal of Current Oncology and Medical Sciences2783-31272024-12-01449901005The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive reviewArman Hamzei0Sara Hallaji1Seyed Farzin Hosseini2Arman Keymoradzadeh3Neuroscience Research Center, School of Medicine, Guilan University of Medical Science, Rasht, IranDepartment of Neurosurgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of Neurosurgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of Neurosurgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, IranGliomas are the most prevalent primary tumors of the brain and spinal cord. Regrettably, the prognosis, especially for high-grade gliomas, remains quite bleak. In recent decades, there's been a growing trend to replace or combine radiotherapy with chemotherapy, targeted therapy, and personalized treatment for different patients. For example, carboplatin and vincristine are considered standard treatments for some patients with unresectable pediatric low-grade gliomas. In recent years, ketogenic diet (KD) has emerged as a promising investigational therapy for CNS tumors, with researchers exploring its use in conjunction with existing treatment modalities. This review article delves into the mechanisms underlying KD's potential therapeutic effects on glioma and its efficacy, safety profile, and overall role in glioma treatment.https://submission.journalofcoms.com/index.php/JCOMS/article/view/248ketogenic dietgliomasmetabolism |
| spellingShingle | Arman Hamzei Sara Hallaji Seyed Farzin Hosseini Arman Keymoradzadeh The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review Journal of Current Oncology and Medical Sciences ketogenic diet gliomas metabolism |
| title | The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review |
| title_full | The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review |
| title_fullStr | The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review |
| title_full_unstemmed | The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review |
| title_short | The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review |
| title_sort | ketogenic diet as a promising adjunctive therapy for glioma a comprehensive review |
| topic | ketogenic diet gliomas metabolism |
| url | https://submission.journalofcoms.com/index.php/JCOMS/article/view/248 |
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