Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients
Hypertension (HTN) remains one of the most important risk factors for cardiovascular events. Modification of additional risk factors, along with a blood pressure decrease, significantly affects the risk of cardiovascular events. Hyperuricemia is one of the new factors that has a high prevalence in t...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2022-09-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/5194 |
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| author | I. A. Libov Yu. N. Moiseeva A. G. Komarova |
| author_facet | I. A. Libov Yu. N. Moiseeva A. G. Komarova |
| author_sort | I. A. Libov |
| collection | DOAJ |
| description | Hypertension (HTN) remains one of the most important risk factors for cardiovascular events. Modification of additional risk factors, along with a blood pressure decrease, significantly affects the risk of cardiovascular events. Hyperuricemia is one of the new factors that has a high prevalence in the population and affects the risk for cardiovascular events in hypertensive patients. In the treatment with fixed-dose combinations in patients with hypertension and hyperuricemia, metabolic neutrality is of particular importance. When prescribing diuretics, the practitioner faces additional difficulties. These drugs are highly synergistic when added to other major antihypertensives’ classes, but, in some cases, may worsen the metabolic profile. The use of the thiazide-like diuretic indapamide largely avoids a negative effect on the metabolic profile, making it the preferred choice for patients with hyperuricemia. |
| format | Article |
| id | doaj-art-80e05bfa6aeb4d72aad2a7e939da859e |
| institution | Kabale University |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2022-09-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-80e05bfa6aeb4d72aad2a7e939da859e2025-08-20T03:57:22Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-09-0127910.15829/1560-4071-2022-51943665Hyperuricemia as a risk factor for cardiovascular events in hypertensive patientsI. A. Libov0Yu. N. Moiseeva1A. G. Komarova2S.P. Botkin Moscow City Clinical HospitalS.P. Botkin Moscow City Clinical HospitalS.P. Botkin Moscow City Clinical HospitalHypertension (HTN) remains one of the most important risk factors for cardiovascular events. Modification of additional risk factors, along with a blood pressure decrease, significantly affects the risk of cardiovascular events. Hyperuricemia is one of the new factors that has a high prevalence in the population and affects the risk for cardiovascular events in hypertensive patients. In the treatment with fixed-dose combinations in patients with hypertension and hyperuricemia, metabolic neutrality is of particular importance. When prescribing diuretics, the practitioner faces additional difficulties. These drugs are highly synergistic when added to other major antihypertensives’ classes, but, in some cases, may worsen the metabolic profile. The use of the thiazide-like diuretic indapamide largely avoids a negative effect on the metabolic profile, making it the preferred choice for patients with hyperuricemia.https://russjcardiol.elpub.ru/jour/article/view/5194hypertensionrisk factorshyperuricemiauric aciddiureticsindapamide |
| spellingShingle | I. A. Libov Yu. N. Moiseeva A. G. Komarova Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients Российский кардиологический журнал hypertension risk factors hyperuricemia uric acid diuretics indapamide |
| title | Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| title_full | Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| title_fullStr | Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| title_full_unstemmed | Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| title_short | Hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| title_sort | hyperuricemia as a risk factor for cardiovascular events in hypertensive patients |
| topic | hypertension risk factors hyperuricemia uric acid diuretics indapamide |
| url | https://russjcardiol.elpub.ru/jour/article/view/5194 |
| work_keys_str_mv | AT ialibov hyperuricemiaasariskfactorforcardiovasculareventsinhypertensivepatients AT yunmoiseeva hyperuricemiaasariskfactorforcardiovasculareventsinhypertensivepatients AT agkomarova hyperuricemiaasariskfactorforcardiovasculareventsinhypertensivepatients |