CHRONIC VIRAL HEPATITIS В AND C IN CHILDREN BORN FROM MOTHERS INFECTED WITH НВV AND HCV
There were 164 children with chronic hepatitis B (CHB) and chronic hepatitis C (CHC) at the age of 1—18 years of age, 78 of which (48%) had a perinatal route of infection (CHB — 46; CHC — 32). Observed for 5 years. Chronic hepatitis B and C was characterized by subclinical signs, with minimal fib...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
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LLC "Diagnostics and Vaccines"
2017-03-01
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| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/271 |
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| Summary: | There were 164 children with chronic hepatitis B (CHB) and chronic hepatitis C (CHC) at the age of 1—18 years of age, 78 of which (48%) had a perinatal route of infection (CHB — 46; CHC — 32). Observed for 5 years. Chronic hepatitis B and C was characterized by subclinical signs, with minimal fibrosis, in the immu- noactive phase of HBV (69%) and high viremia HCV (56%). Etiopathogenetic therapy (alpha-2b interferon (VIFERON, PegIntron), lamivudine (Zeffix), ribavirin (Rebetol) promoted the development of clinico-virologic remission in 83% of children with CHB and 63% in CHC. |
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| ISSN: | 2072-8107 |