A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine

Thyroglobulin (Tg) is an important modality for monitoring patients with thyroid cancers, especially after thyroidectomy followed by radioiodine (RAI). It is also used as a marker for burden of thyroid tissue whether malignant or benign. Although there have been several reports of rising serum Tg tr...

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Main Authors: Mandana Moosavi, Stuart Kreisman
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2016/6471081
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author Mandana Moosavi
Stuart Kreisman
author_facet Mandana Moosavi
Stuart Kreisman
author_sort Mandana Moosavi
collection DOAJ
description Thyroglobulin (Tg) is an important modality for monitoring patients with thyroid cancers, especially after thyroidectomy followed by radioiodine (RAI). It is also used as a marker for burden of thyroid tissue whether malignant or benign. Although there have been several reports of rising serum Tg transiently after thyroid biopsy in intact glands and following palpation or trauma, there are no reports in the literature of elevation in Tg after biopsy of suspicious lesions in thyroidectomized patients. In this paper we report a fascinating case of a considerable and initially worrying, although ultimately transient, rise in Tg in a patient 2 years after total thyroidectomy and RAI ablation after fine needle aspiration (FNA) of a suspicious thyroid bed nodule that was proven positive.
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spelling doaj-art-80cdd4b8ffc14a4cb92df7372e1464022025-02-03T01:27:44ZengWileyCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/64710816471081A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and RadioiodineMandana Moosavi0Stuart Kreisman1Vancouver Coastal Health, CanadaDivision of Endocrinology, St. Paul’s Hospital, 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, CanadaThyroglobulin (Tg) is an important modality for monitoring patients with thyroid cancers, especially after thyroidectomy followed by radioiodine (RAI). It is also used as a marker for burden of thyroid tissue whether malignant or benign. Although there have been several reports of rising serum Tg transiently after thyroid biopsy in intact glands and following palpation or trauma, there are no reports in the literature of elevation in Tg after biopsy of suspicious lesions in thyroidectomized patients. In this paper we report a fascinating case of a considerable and initially worrying, although ultimately transient, rise in Tg in a patient 2 years after total thyroidectomy and RAI ablation after fine needle aspiration (FNA) of a suspicious thyroid bed nodule that was proven positive.http://dx.doi.org/10.1155/2016/6471081
spellingShingle Mandana Moosavi
Stuart Kreisman
A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
Case Reports in Endocrinology
title A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
title_full A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
title_fullStr A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
title_full_unstemmed A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
title_short A Case Report of Dramatically Increased Thyroglobulin after Lymph Node Biopsy in Thyroid Carcinoma after Total Thyroidectomy and Radioiodine
title_sort case report of dramatically increased thyroglobulin after lymph node biopsy in thyroid carcinoma after total thyroidectomy and radioiodine
url http://dx.doi.org/10.1155/2016/6471081
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