Electrostatic mis-interactions cause overexpression toxicity of proteins in E. coli.

A majority of E. coli proteins when overexpressed inhibit its growth, but the reasons behind overexpression toxicity of proteins remain unknown. Understanding the mechanism of overexpression toxicity is important from evolutionary, biotechnological and possibly clinical perspectives. Here we study s...

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Bibliographic Details
Main Authors: Gajinder Pal Singh, Debasis Dash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0064893&type=printable
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