Role of calcineurin and ionotropic glutamate receptors in Alzheimer's disease: A systematic review

Role of calcineurin and ionotropic glutamate receptors in Alzheimer's disease: A systematic review

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and behavioral changes. Calcineurin (CaN), a calcium/calmodulin-dependent serine/threonine phosphatase, is hyperactivated in AD, leading to enhanced neuroinflammation, synaptic...

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Main Authors:	Awgichew Behaile Teklemariam, Edgeit Abebe Zewde, Melaku Mekonnen Agidew, Sisay Ayalkibet Siyamrew, Lemlemu Maru, Zelalem Tilahun Muche
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Series:	Brain Disorders
Subjects:	Alzheimer's disease AMPA Calcineurin iGluRs Kainate receptors NMDA
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666459325000381
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