Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study

Objectives Cognitive-behavioral stress management (CBSM) is an effective psychological intervention to relieve psychological and symptomatic distress. This study aimed to investigate the effect of CBSM in anxiety, depression, and post-traumatic stress disorder (PTSD) in parents of pediatric acute my...

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Main Authors: Li Wang, Hui Duan, Hongmei Zuo, Zhongyu Wang, Shuili Jiao, Yanli Liu, Huihui Li, Jie Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
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Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2023.2293498
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author Li Wang
Hui Duan
Hongmei Zuo
Zhongyu Wang
Shuili Jiao
Yanli Liu
Huihui Li
Jie Chen
author_facet Li Wang
Hui Duan
Hongmei Zuo
Zhongyu Wang
Shuili Jiao
Yanli Liu
Huihui Li
Jie Chen
author_sort Li Wang
collection DOAJ
description Objectives Cognitive-behavioral stress management (CBSM) is an effective psychological intervention to relieve psychological and symptomatic distress. This study aimed to investigate the effect of CBSM in anxiety, depression, and post-traumatic stress disorder (PTSD) in parents of pediatric acute myeloid leukemia (AML) patients.Methods Totally, 56 pediatric AML patients and 100 parents were randomized into the CBSM group (28 patients and 49 parents) and the normal control (NC) group (28 patients and 51 parents) to receive corresponding interventions for 10 weeks. The questionnaire scores were assessed at month M0, M1, M3, and M6.Results In parents of pediatric AML patients, self-rating anxiety scale score at M1 (p = 0.034), M3 (p = 0.010), and M6 (p = 0.003), as well as anxiety at M3 (p = 0.036) and M6 (p = 0.012) were decreased in the CBSM group versus the NC group. Self-rating depression scale score at M3 (p = 0.022) and M6 (p = 0.002), as well as depression at M6 (p = 0.019) were declined in the CBSM group versus the NC group. Symptom checklist-90 (a psychotic status questionnaire) score at M3 (p = 0.031) and M6 (p = 0.019) were declined in the CBSM group versus the NC group. Regarding PTSD, the impact of the events scale-revised score at M3 (p = 0.044) and M6 (p = 0.010) were decreased in the CBSM group versus the NC group. By subgroup analyses CBSM (versus NC) improved all outcomes in parents with anxiety at M0 and depression at M0 (all p < 0.050), but could not affect the outcomes in parents without anxiety or depression at M0 (all p > 0.050).Conclusion CBSM reduces anxiety, depression, and PTSD in parents of pediatric AML patients.
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spelling doaj-art-80c2bdd5748841ea96d158daa6bca0ab2025-08-20T02:34:31ZengTaylor & Francis GroupHematology1607-84542024-12-0129110.1080/16078454.2023.2293498Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled studyLi Wang0Hui Duan1Hongmei Zuo2Zhongyu Wang3Shuili Jiao4Yanli Liu5Huihui Li6Jie Chen7Department of Pediatrics, Affiliated Hospital of Hebei Engineering University, Handan, People’s Republic of ChinaDepartment of Pediatrics, Affiliated Hospital of Hebei Engineering University, Handan, People’s Republic of ChinaDepartment of Pediatrics, Affiliated Hospital of Hebei Engineering University, Handan, People’s Republic of ChinaDepartment of Oncology, Handan Central Hospital, Handan, People’s Republic of ChinaDepartment of Pediatrics Ward 2, Handan Central Hospital, Handan, People’s Republic of ChinaDepartment of Neonatology Ward 1, Handan Central Hospital, Handan, People’s Republic of ChinaDepartment of Neonatology Ward 1, Handan Central Hospital, Handan, People’s Republic of ChinaDepartment of Nephrology 2, Handan Central Hospital, Handan, People’s Republic of ChinaObjectives Cognitive-behavioral stress management (CBSM) is an effective psychological intervention to relieve psychological and symptomatic distress. This study aimed to investigate the effect of CBSM in anxiety, depression, and post-traumatic stress disorder (PTSD) in parents of pediatric acute myeloid leukemia (AML) patients.Methods Totally, 56 pediatric AML patients and 100 parents were randomized into the CBSM group (28 patients and 49 parents) and the normal control (NC) group (28 patients and 51 parents) to receive corresponding interventions for 10 weeks. The questionnaire scores were assessed at month M0, M1, M3, and M6.Results In parents of pediatric AML patients, self-rating anxiety scale score at M1 (p = 0.034), M3 (p = 0.010), and M6 (p = 0.003), as well as anxiety at M3 (p = 0.036) and M6 (p = 0.012) were decreased in the CBSM group versus the NC group. Self-rating depression scale score at M3 (p = 0.022) and M6 (p = 0.002), as well as depression at M6 (p = 0.019) were declined in the CBSM group versus the NC group. Symptom checklist-90 (a psychotic status questionnaire) score at M3 (p = 0.031) and M6 (p = 0.019) were declined in the CBSM group versus the NC group. Regarding PTSD, the impact of the events scale-revised score at M3 (p = 0.044) and M6 (p = 0.010) were decreased in the CBSM group versus the NC group. By subgroup analyses CBSM (versus NC) improved all outcomes in parents with anxiety at M0 and depression at M0 (all p < 0.050), but could not affect the outcomes in parents without anxiety or depression at M0 (all p > 0.050).Conclusion CBSM reduces anxiety, depression, and PTSD in parents of pediatric AML patients.https://www.tandfonline.com/doi/10.1080/16078454.2023.2293498Cognitive-behavioral stress managementparentspediatric acute myeloid leukemiaanxiety and depressionpost-traumatic stress disorder
spellingShingle Li Wang
Hui Duan
Hongmei Zuo
Zhongyu Wang
Shuili Jiao
Yanli Liu
Huihui Li
Jie Chen
Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
Hematology
Cognitive-behavioral stress management
parents
pediatric acute myeloid leukemia
anxiety and depression
post-traumatic stress disorder
title Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
title_full Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
title_fullStr Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
title_full_unstemmed Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
title_short Cognitive-behavioral stress management relieves anxiety, depression, and post-traumatic stress disorder in parents of pediatric acute myeloid leukemia patients: a randomized, controlled study
title_sort cognitive behavioral stress management relieves anxiety depression and post traumatic stress disorder in parents of pediatric acute myeloid leukemia patients a randomized controlled study
topic Cognitive-behavioral stress management
parents
pediatric acute myeloid leukemia
anxiety and depression
post-traumatic stress disorder
url https://www.tandfonline.com/doi/10.1080/16078454.2023.2293498
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