New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy

New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy

Background and purpose: Growing evidence suggests that spatial dose variations across the rectal surface influence toxicity risk after radiotherapy. Existing methodologies employ a fixed, arbitrary physical extent for rectal dose mapping, limiting their analysis. We developed a method to standardise...

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Main Authors: Artemis Bouzaki, Dylan Green, Marcel van Herk, Jane Shortall, Tanuj Puri, Sarah Kerns, David Azria, Marrie-Pierre Farcy-Jacquet, Jenny Chang-Claude, Ananya Choudhury, Alison Dunning, Maarten Lambrecht, Barbara Avuzzi, Dirk De Ruysscher, Petra Seibold, Elena Sperk, Christopher Talbot, Ana Vega, Liv Veldeman, Adam Webb, Barry Rosenstein, Catharine M. West, Eliana Gioscio, Tiziana Rancati, Eliana Vasquez Osorio, Alan McWilliam
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Physics and Imaging in Radiation Oncology
Subjects:
Radiotherapy
Prostate cancer
Normal tissue toxicity
Dose surface map
Rectum mapping
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631625000065
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