Association between cognitive impairment and criteria for frailty syndrome among older adults

Abstract The association between cognitive impairment and physical frailty has been studied in older adults. The criteria degree of frailty may be keys to associated cognitive impairment. Objective: To analyze the association between cognitive impairment and the criteria for frailty. Methods: We...

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Main Authors: Allan Gustavo BRIGOLA, Ana Carolina OTTAVIANI, Danilo Henrique Trevisan CARVALHO, Nathalia Alves OLIVEIRA, Érica Nestor SOUZA, Sofia Cristina Iost PAVARINI
Format: Article
Language:English
Published: Thieme Revinter Publicações 2020-01-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000100002&tlng=en
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author Allan Gustavo BRIGOLA
Ana Carolina OTTAVIANI
Danilo Henrique Trevisan CARVALHO
Nathalia Alves OLIVEIRA
Érica Nestor SOUZA
Sofia Cristina Iost PAVARINI
author_facet Allan Gustavo BRIGOLA
Ana Carolina OTTAVIANI
Danilo Henrique Trevisan CARVALHO
Nathalia Alves OLIVEIRA
Érica Nestor SOUZA
Sofia Cristina Iost PAVARINI
author_sort Allan Gustavo BRIGOLA
collection DOAJ
description Abstract The association between cognitive impairment and physical frailty has been studied in older adults. The criteria degree of frailty may be keys to associated cognitive impairment. Objective: To analyze the association between cognitive impairment and the criteria for frailty. Methods: We cross-sectionally examined data from 667 older adults (≥60 years of age) from a study entitled ‘Variables associated to cognition in elderly caregivers’ involving patients in an urban and rural primary healthcare center. We defined cognitive impairment based on different groups of scores on the Mini Mental State Examination, and defined frailty and prefrailty using the criteria by the Cardiovascular Health Study. We performed multinomial regression models to analyze the association between levels of frailty and cognitive impairment. Results: Similar proportions of women (54.8%) and men (45.2%) participated in the study (mean age: 71 years old). We found cognitive impairment, prefrailty and frailty in 34, 54, and 24% of the participants, respectively. Concomitant cognitive impairment and frailty was found in 13% of them. The chances of cognitive impairment increased up to 330% (Odds Ratio [OR]: 4.3; 95% confidence interval [95%CI] 2.4‒7.7; p<0.001) among frail individuals, and 70% (OR: 1.7; 95%CI 1.0‒2.8; p=0.033) among prefrail individuals compared to robust/non-frail individuals. After controlling for age, education, place of residence and functional dependence, slowness and fatigue criteria were significantly associated with cognitive impairment. Conclusion: Older adults with frailty have a greater likelihood of concomitant cognitive impairment than prefrail and robust older adults. The prevalence of cognitive impairment and frailty is consistent with data reported in literature. The present findings contribute to the investigation of cognitive frailty.
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spelling doaj-art-80b72ef6085c47a1851b319b454ecc2c2025-08-20T03:06:57ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272020-01-017812810.1590/0004-282x20190138Association between cognitive impairment and criteria for frailty syndrome among older adultsAllan Gustavo BRIGOLAhttps://orcid.org/0000-0003-0265-4940Ana Carolina OTTAVIANIhttps://orcid.org/0000-0003-4037-4587Danilo Henrique Trevisan CARVALHOhttps://orcid.org/0000-0002-1089-5739Nathalia Alves OLIVEIRAhttps://orcid.org/0000-0003-1665-8109Érica Nestor SOUZAhttps://orcid.org/0000-0002-7952-7643Sofia Cristina Iost PAVARINIhttps://orcid.org/0000-0001-9359-8600Abstract The association between cognitive impairment and physical frailty has been studied in older adults. The criteria degree of frailty may be keys to associated cognitive impairment. Objective: To analyze the association between cognitive impairment and the criteria for frailty. Methods: We cross-sectionally examined data from 667 older adults (≥60 years of age) from a study entitled ‘Variables associated to cognition in elderly caregivers’ involving patients in an urban and rural primary healthcare center. We defined cognitive impairment based on different groups of scores on the Mini Mental State Examination, and defined frailty and prefrailty using the criteria by the Cardiovascular Health Study. We performed multinomial regression models to analyze the association between levels of frailty and cognitive impairment. Results: Similar proportions of women (54.8%) and men (45.2%) participated in the study (mean age: 71 years old). We found cognitive impairment, prefrailty and frailty in 34, 54, and 24% of the participants, respectively. Concomitant cognitive impairment and frailty was found in 13% of them. The chances of cognitive impairment increased up to 330% (Odds Ratio [OR]: 4.3; 95% confidence interval [95%CI] 2.4‒7.7; p<0.001) among frail individuals, and 70% (OR: 1.7; 95%CI 1.0‒2.8; p=0.033) among prefrail individuals compared to robust/non-frail individuals. After controlling for age, education, place of residence and functional dependence, slowness and fatigue criteria were significantly associated with cognitive impairment. Conclusion: Older adults with frailty have a greater likelihood of concomitant cognitive impairment than prefrail and robust older adults. The prevalence of cognitive impairment and frailty is consistent with data reported in literature. The present findings contribute to the investigation of cognitive frailty.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000100002&tlng=enolder adultscognitive dysfunctionfrailty
spellingShingle Allan Gustavo BRIGOLA
Ana Carolina OTTAVIANI
Danilo Henrique Trevisan CARVALHO
Nathalia Alves OLIVEIRA
Érica Nestor SOUZA
Sofia Cristina Iost PAVARINI
Association between cognitive impairment and criteria for frailty syndrome among older adults
Arquivos de Neuro-Psiquiatria
older adults
cognitive dysfunction
frailty
title Association between cognitive impairment and criteria for frailty syndrome among older adults
title_full Association between cognitive impairment and criteria for frailty syndrome among older adults
title_fullStr Association between cognitive impairment and criteria for frailty syndrome among older adults
title_full_unstemmed Association between cognitive impairment and criteria for frailty syndrome among older adults
title_short Association between cognitive impairment and criteria for frailty syndrome among older adults
title_sort association between cognitive impairment and criteria for frailty syndrome among older adults
topic older adults
cognitive dysfunction
frailty
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000100002&tlng=en
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