The influence of different forms of apple products on all-cause mortality in patients with hypertension

ObjectiveApple consumption has a positive effect on human health. Some studies have shown that an appropriate amount of apple intake can reduce the incidence of hypertension. However, few studies have investigated whether eating different forms of apples has the same benefits as eating whole apples....

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Main Authors: Chuang Sun, Yingying Chen, Yue Guan, Yiming Zeng, Jie Li, Liang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1461196/full
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author Chuang Sun
Yingying Chen
Yue Guan
Yiming Zeng
Jie Li
Liang Chen
author_facet Chuang Sun
Yingying Chen
Yue Guan
Yiming Zeng
Jie Li
Liang Chen
author_sort Chuang Sun
collection DOAJ
description ObjectiveApple consumption has a positive effect on human health. Some studies have shown that an appropriate amount of apple intake can reduce the incidence of hypertension. However, few studies have investigated whether eating different forms of apples has the same benefits as eating whole apples. This study is aimed to evaluate the effect of different forms of apple on all-cause mortality in patients with hypertension.MethodsThe study included 2,368 patients with hypertension. All participants were followed up for at least 10 years. Cox regression model was constructed to analyze the correlation between apple, apple juice, and apple sauce consumption and all-cause mortality in patients with hypertension.ResultsThe consumption of apples 3–6 times/week was associated with a 48% reduction in the risk of all-cause mortality in patients with hypertension (HR = 0.52, 95% CI: 0.37–0.72, p < 0.001). However, the consumption of apple juice (HR = 1.02, 95% CI: 0.67–1.56, p = 0.930) and sauce (HR = 1.28, 95% CI: 0.59–2.74, p = 0.531) tended to increase the risk of death in patients with hypertension, although this study did not obtain a statistically result.ConclusionModerate consumption of whole apples is associated with a reduced risk of all-cause death in patients with hypertension, whereas apple juice and sauce may increase the risk of death.
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spelling doaj-art-80b2a61c044940e5a82504b22f6befa42025-01-24T05:21:23ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-01-011110.3389/fnut.2024.14611961461196The influence of different forms of apple products on all-cause mortality in patients with hypertensionChuang Sun0Yingying Chen1Yue Guan2Yiming Zeng3Jie Li4Liang Chen5Department of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Internal Medicine, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Internal Medicine, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, ChinaDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaObjectiveApple consumption has a positive effect on human health. Some studies have shown that an appropriate amount of apple intake can reduce the incidence of hypertension. However, few studies have investigated whether eating different forms of apples has the same benefits as eating whole apples. This study is aimed to evaluate the effect of different forms of apple on all-cause mortality in patients with hypertension.MethodsThe study included 2,368 patients with hypertension. All participants were followed up for at least 10 years. Cox regression model was constructed to analyze the correlation between apple, apple juice, and apple sauce consumption and all-cause mortality in patients with hypertension.ResultsThe consumption of apples 3–6 times/week was associated with a 48% reduction in the risk of all-cause mortality in patients with hypertension (HR = 0.52, 95% CI: 0.37–0.72, p < 0.001). However, the consumption of apple juice (HR = 1.02, 95% CI: 0.67–1.56, p = 0.930) and sauce (HR = 1.28, 95% CI: 0.59–2.74, p = 0.531) tended to increase the risk of death in patients with hypertension, although this study did not obtain a statistically result.ConclusionModerate consumption of whole apples is associated with a reduced risk of all-cause death in patients with hypertension, whereas apple juice and sauce may increase the risk of death.https://www.frontiersin.org/articles/10.3389/fnut.2024.1461196/fullapple consumptionapple productshypertensionmortalityNHANES
spellingShingle Chuang Sun
Yingying Chen
Yue Guan
Yiming Zeng
Jie Li
Liang Chen
The influence of different forms of apple products on all-cause mortality in patients with hypertension
Frontiers in Nutrition
apple consumption
apple products
hypertension
mortality
NHANES
title The influence of different forms of apple products on all-cause mortality in patients with hypertension
title_full The influence of different forms of apple products on all-cause mortality in patients with hypertension
title_fullStr The influence of different forms of apple products on all-cause mortality in patients with hypertension
title_full_unstemmed The influence of different forms of apple products on all-cause mortality in patients with hypertension
title_short The influence of different forms of apple products on all-cause mortality in patients with hypertension
title_sort influence of different forms of apple products on all cause mortality in patients with hypertension
topic apple consumption
apple products
hypertension
mortality
NHANES
url https://www.frontiersin.org/articles/10.3389/fnut.2024.1461196/full
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