Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning

Abstract Background Children with acute leukaemia often have adverse social adaptive behaviors during treatment, and good social support and family function are considered to be important protection factors. However, little is known about the interaction mechanism of social adaptive behaviors, socia...

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Main Authors: Shen Yuqing, Mo Lin, Yu Lu, Chen ZeFang, Liu Tao, Zeng Yan, Sabika
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s12887-025-05775-6
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author Shen Yuqing
Mo Lin
Yu Lu
Chen ZeFang
Liu Tao
Zeng Yan
Sabika
author_facet Shen Yuqing
Mo Lin
Yu Lu
Chen ZeFang
Liu Tao
Zeng Yan
Sabika
author_sort Shen Yuqing
collection DOAJ
description Abstract Background Children with acute leukaemia often have adverse social adaptive behaviors during treatment, and good social support and family function are considered to be important protection factors. However, little is known about the interaction mechanism of social adaptive behaviors, social support and family function in children with acute leukaemia. This study aimed to explore the mediating role of family function in social support and social adaptive behaviors of children with acute leukemia in China. Methods From August to December 2022, face-to-face data collection was conducted using convenience sampling in the Blood Department of a 3 A Children’s Hospital in Chongqing, China. A total of 202 caregivers of children with acute leukemia participated in the questionnaire. Children’s Adaptive Behavior Scale, family function scale and social support scale were used for evaluation. AMOS 26.0 structural equation modelling method was adopted, and Pearson correlation analysis and deviation-corrected centile Bootstrap method were adopted for analysis. Results Among the 202 participants, 22.77% (46/202) of the children with acute leukaemia showed adverse social adaptive behaviors. Social support, family functioning and social adaptive behaviors demonstrated significant correlations(r = 0.318、-0.392,p < 0.05). It is worth noting that family functioning has a full mediating effect on social support and social adaptive behaviors. Conclusions The evidence provided by this study indicates that social support can positively predict social adaptive behaviors, family functioning can negatively predict social adaptive behaviors, and family functioning mediates the relationship between social support and social adaptive behaviors.This study attributes to the development of precise interventions for caregivers for socially adapted behaviours in children with acute leukaemia and has important implications for policy development to improve the social adaptation of children with leukaemia.
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spelling doaj-art-80afd08e0f2345fba58dd9744e72cd3a2025-08-20T02:05:16ZengBMCBMC Pediatrics1471-24312025-06-0125111210.1186/s12887-025-05775-6Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioningShen Yuqing0Mo Lin1Yu Lu2Chen ZeFang3Liu Tao4Zeng Yan5Sabika6School of Nursing, Chongqing Medical UniversityDepartment of Nursing, Children’s Hospital of Chongqing Medical UniversityKey Laboratory of the Ministry of Education for the Study of Childhood Developmental DiseasesSchool of Nursing, Chongqing Medical UniversitySchool of Nursing, Chongqing Medical UniversitySchool of Nursing, Chongqing Medical UniversityCollage of Teacher Education, Zhejiang Normal UniversityAbstract Background Children with acute leukaemia often have adverse social adaptive behaviors during treatment, and good social support and family function are considered to be important protection factors. However, little is known about the interaction mechanism of social adaptive behaviors, social support and family function in children with acute leukaemia. This study aimed to explore the mediating role of family function in social support and social adaptive behaviors of children with acute leukemia in China. Methods From August to December 2022, face-to-face data collection was conducted using convenience sampling in the Blood Department of a 3 A Children’s Hospital in Chongqing, China. A total of 202 caregivers of children with acute leukemia participated in the questionnaire. Children’s Adaptive Behavior Scale, family function scale and social support scale were used for evaluation. AMOS 26.0 structural equation modelling method was adopted, and Pearson correlation analysis and deviation-corrected centile Bootstrap method were adopted for analysis. Results Among the 202 participants, 22.77% (46/202) of the children with acute leukaemia showed adverse social adaptive behaviors. Social support, family functioning and social adaptive behaviors demonstrated significant correlations(r = 0.318、-0.392,p < 0.05). It is worth noting that family functioning has a full mediating effect on social support and social adaptive behaviors. Conclusions The evidence provided by this study indicates that social support can positively predict social adaptive behaviors, family functioning can negatively predict social adaptive behaviors, and family functioning mediates the relationship between social support and social adaptive behaviors.This study attributes to the development of precise interventions for caregivers for socially adapted behaviours in children with acute leukaemia and has important implications for policy development to improve the social adaptation of children with leukaemia.https://doi.org/10.1186/s12887-025-05775-6Acute leukemiaChildrenSocial adaptive behaviorsSocial supportStructural equation model(SEM)
spellingShingle Shen Yuqing
Mo Lin
Yu Lu
Chen ZeFang
Liu Tao
Zeng Yan
Sabika
Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
BMC Pediatrics
Acute leukemia
Children
Social adaptive behaviors
Social support
Structural equation model(SEM)
title Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
title_full Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
title_fullStr Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
title_full_unstemmed Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
title_short Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning
title_sort influence of social support on the social adaptive behaviors of children with acute leukemia in china the mediating role of family functioning
topic Acute leukemia
Children
Social adaptive behaviors
Social support
Structural equation model(SEM)
url https://doi.org/10.1186/s12887-025-05775-6
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