Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults
ObjectiveLower limb muscle mass (LLMM) accounts for more than 50% of the total body skeletal muscle mass. Assessing leg muscle mass in middle-aged and elderly individuals is crucial for the prevention and diagnosis of sarcopenia. Current bioelectrical impedance analysis (BIA) devices are capable of...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2025.1546499/full |
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| author | Ai-Chun Huang Hsueh-Kuan Lu Chien-Wei Liang Kuen-Chang Hsieh Kuen-Chang Hsieh Yi-Sung Tsai Chung-Liang Lai Chung-Liang Lai |
| author_facet | Ai-Chun Huang Hsueh-Kuan Lu Chien-Wei Liang Kuen-Chang Hsieh Kuen-Chang Hsieh Yi-Sung Tsai Chung-Liang Lai Chung-Liang Lai |
| author_sort | Ai-Chun Huang |
| collection | DOAJ |
| description | ObjectiveLower limb muscle mass (LLMM) accounts for more than 50% of the total body skeletal muscle mass. Assessing leg muscle mass in middle-aged and elderly individuals is crucial for the prevention and diagnosis of sarcopenia. Current bioelectrical impedance analysis (BIA) devices are capable of measuring LLMM, but validation studies are limited. This study compares the accuracy of BIA devices with different frequencies for measuring LLMM in middle-aged and elderly populations.MethodsLLMM measurements were obtained using the following devices: foot-to-foot dual-frequency (StarBIA201, 5, 50 KHz), multi-segment single-frequency (Tanita BC418, 50 KHz), dual-frequency (InBody270, 20, 100 KHz), triple-frequency (Tanita MC780MA, 5, 50, 250 KHz), and six-frequency (InBody770, 1, 5, 50, 250, 500, 1,000 KHz). Dual-energy X-ray absorptiometry (DXA) served as the reference standard. Comparisons were conducted using the following metrics: (1) mean difference (bias), (2) limits of agreement (LOA), (3) Pearson correlation coefficients, and (4) ordinary least product (OLP) regression analysis.ResultsA total of 153 community-dwelling individuals aged over 55 years (102 females, 51 males) were recruited. The average age of participants was 67.5 ± 8.9 years, with a BMI of 23.9 ± 3.9 kg/m2 and a body fat percentage of 35.8 ± 6.5%. The correlation coefficients of StarBIA201, BC418, InBody270, MC780, and InBody770 with DXA were 0.902, 0.903, 0.917, 0.925, and 0.928, respectively. Their mean differences were −0.141, −2.731, −0.587, −1.613, and −0.625 kg, with LOAs of 4.3, 5.7, 4.0, 5.1, and 3.8 kg, respectively. StarBIA201 and InBody270 showed no fixed or proportional biases.ConclusionThis study demonstrates that the four-electrode foot-to-foot BIA method shows significant practicality and potential in assessing LLMM. Compared to multi-frequency BIA and DXA, this method is simpler to operate and more convenient, making it particularly suitable for preliminary screening and assessment of sarcopenia in clinical and community settings. |
| format | Article |
| id | doaj-art-80ad8491d1404a07a2046569b0567883 |
| institution | Kabale University |
| issn | 2296-861X |
| language | English |
| publishDate | 2025-02-01 |
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| series | Frontiers in Nutrition |
| spelling | doaj-art-80ad8491d1404a07a2046569b05678832025-02-07T05:10:34ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2025-02-011210.3389/fnut.2025.15464991546499Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adultsAi-Chun Huang0Hsueh-Kuan Lu1Chien-Wei Liang2Kuen-Chang Hsieh3Kuen-Chang Hsieh4Yi-Sung Tsai5Chung-Liang Lai6Chung-Liang Lai7Physical Education and Health Center, National Kaohsiung University of Hospitality and Tourism, Kaohsiung, TaiwanGeneral Education Center, National Taiwan University of Sport, Taichung, TaiwanOffice and Physical Education and Sport, National Chung Hsing University, Taichung, TaiwanDepartment of Research and Development, Starbia Meditek Co., Ltd, Taichung, TaiwanBig Data Center, National Chung-Hsing University, Taichung, TaiwanDepartment of Physical Medicine and Rehabilitation, Taichung Hospital, Ministry of Health and Welfare, Taichung, TaiwanDepartment of Physical Medicine and Rehabilitation, Puzi Hospital, Ministry of Health and Welfare, Chiayi, TaiwanDepartment of Occupational Therapy, Asia University, Taichung, TaiwanObjectiveLower limb muscle mass (LLMM) accounts for more than 50% of the total body skeletal muscle mass. Assessing leg muscle mass in middle-aged and elderly individuals is crucial for the prevention and diagnosis of sarcopenia. Current bioelectrical impedance analysis (BIA) devices are capable of measuring LLMM, but validation studies are limited. This study compares the accuracy of BIA devices with different frequencies for measuring LLMM in middle-aged and elderly populations.MethodsLLMM measurements were obtained using the following devices: foot-to-foot dual-frequency (StarBIA201, 5, 50 KHz), multi-segment single-frequency (Tanita BC418, 50 KHz), dual-frequency (InBody270, 20, 100 KHz), triple-frequency (Tanita MC780MA, 5, 50, 250 KHz), and six-frequency (InBody770, 1, 5, 50, 250, 500, 1,000 KHz). Dual-energy X-ray absorptiometry (DXA) served as the reference standard. Comparisons were conducted using the following metrics: (1) mean difference (bias), (2) limits of agreement (LOA), (3) Pearson correlation coefficients, and (4) ordinary least product (OLP) regression analysis.ResultsA total of 153 community-dwelling individuals aged over 55 years (102 females, 51 males) were recruited. The average age of participants was 67.5 ± 8.9 years, with a BMI of 23.9 ± 3.9 kg/m2 and a body fat percentage of 35.8 ± 6.5%. The correlation coefficients of StarBIA201, BC418, InBody270, MC780, and InBody770 with DXA were 0.902, 0.903, 0.917, 0.925, and 0.928, respectively. Their mean differences were −0.141, −2.731, −0.587, −1.613, and −0.625 kg, with LOAs of 4.3, 5.7, 4.0, 5.1, and 3.8 kg, respectively. StarBIA201 and InBody270 showed no fixed or proportional biases.ConclusionThis study demonstrates that the four-electrode foot-to-foot BIA method shows significant practicality and potential in assessing LLMM. Compared to multi-frequency BIA and DXA, this method is simpler to operate and more convenient, making it particularly suitable for preliminary screening and assessment of sarcopenia in clinical and community settings.https://www.frontiersin.org/articles/10.3389/fnut.2025.1546499/fullsarcopeniadual-energy X-ray absorptiometrybioelectrical impedancebioelectrical impedance analysisskeletal muscle mass |
| spellingShingle | Ai-Chun Huang Hsueh-Kuan Lu Chien-Wei Liang Kuen-Chang Hsieh Kuen-Chang Hsieh Yi-Sung Tsai Chung-Liang Lai Chung-Liang Lai Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults Frontiers in Nutrition sarcopenia dual-energy X-ray absorptiometry bioelectrical impedance bioelectrical impedance analysis skeletal muscle mass |
| title | Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults |
| title_full | Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults |
| title_fullStr | Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults |
| title_full_unstemmed | Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults |
| title_short | Comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle-aged and elderly adults |
| title_sort | comparison study of bioelectrical impedance analyzers for measuring lower limb muscle mass in middle aged and elderly adults |
| topic | sarcopenia dual-energy X-ray absorptiometry bioelectrical impedance bioelectrical impedance analysis skeletal muscle mass |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2025.1546499/full |
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