Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)
Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight agains...
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| Format: | Article |
| Language: | Russian |
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Practical Medicine Publishing House
2019-03-01
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| Series: | Клиническая онкогематология |
| Subjects: | |
| Online Access: |
http://bloodjournal.ru/wp-content/uploads/2019/03/3-3.pdf
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| _version_ | 1850251251887898624 |
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| author | ON Solopova VA Misyurin |
| author_facet | ON Solopova VA Misyurin |
| author_sort | ON Solopova |
| collection | DOAJ |
| description | Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight against tumor. The present review covers all the formats and strategies used in engineering of bispecific antibodies which reached the stage of clinical trials and also focuses on the available results of these clinical trials. |
| format | Article |
| id | doaj-art-80a3c10d6d894ef5ba03f2a60973dd4b |
| institution | OA Journals |
| issn | 1997-6933 2500-2139 |
| language | Russian |
| publishDate | 2019-03-01 |
| publisher | Practical Medicine Publishing House |
| record_format | Article |
| series | Клиническая онкогематология |
| spelling | doaj-art-80a3c10d6d894ef5ba03f2a60973dd4b2025-08-20T01:57:56ZrusPractical Medicine Publishing HouseКлиническая онкогематология1997-69332500-21392019-03-0112212514410.21320/2500-2139-2019-12-2-125-14419976933Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)ON Solopova0VA Misyurin1 NN Blokhin National Medical Cancer Research Center, 24 Kashirskoye sh., Moscow, Russian Federation, 115478 NN Blokhin National Medical Cancer Research Center, 24 Kashirskoye sh., Moscow, Russian Federation, 115478 Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight against tumor. The present review covers all the formats and strategies used in engineering of bispecific antibodies which reached the stage of clinical trials and also focuses on the available results of these clinical trials. http://bloodjournal.ru/wp-content/uploads/2019/03/3-3.pdf bispecific antibodiesblinatumomabcatumaxomabemicizumabclinical trial |
| spellingShingle | ON Solopova VA Misyurin Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) Клиническая онкогематология bispecific antibodies blinatumomab catumaxomab emicizumab clinical trial |
| title | Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) |
| title_full | Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) |
| title_fullStr | Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) |
| title_full_unstemmed | Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) |
| title_short | Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review) |
| title_sort | bispecific antibodies in clinical practice and clinical trials literature review |
| topic | bispecific antibodies blinatumomab catumaxomab emicizumab clinical trial |
| url |
http://bloodjournal.ru/wp-content/uploads/2019/03/3-3.pdf
|
| work_keys_str_mv | AT onsolopova bispecificantibodiesinclinicalpracticeandclinicaltrialsliteraturereview AT vamisyurin bispecificantibodiesinclinicalpracticeandclinicaltrialsliteraturereview |