Bispecific Antibodies in Clinical Practice and Clinical Trials (Literature Review)

Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight agains...

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Bibliographic Details
Main Authors: ON Solopova, VA Misyurin
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2019-03-01
Series:Клиническая онкогематология
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Online Access: http://bloodjournal.ru/wp-content/uploads/2019/03/3-3.pdf
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Summary:Therapeutic monoclonal antibodies have long been an effective tool deployed by physicians of different specialties, particularly by oncologists. Bispecific antibodies opened up new horizons in the treatment of cancer as they allow to involve a patient’s endogenous immunity in his or her fight against tumor. The present review covers all the formats and strategies used in engineering of bispecific antibodies which reached the stage of clinical trials and also focuses on the available results of these clinical trials.
ISSN:1997-6933
2500-2139