Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas

Abstract Background To assess the effectiveness of the IraPEN program in decreasing the risk of cardiovascular disease (CVD) and associated risk factors in selected areas of Iran. Methods A secondary data analysis of longitudinal data collected between 2016 and 2017 from health centers in four pilot...

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Main Authors: Somayeh Derakhshan, Davood Khalili, Alireza Mahdavi, Seyed-Saeed Hashemi-Nazari, Amir Kavousi, Fatemeh Hadavandsiri, Afshin Ostovar, Koorosh Etemad
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Language:English
Published: BMC 2025-02-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-024-21168-3
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author Somayeh Derakhshan
Davood Khalili
Alireza Mahdavi
Seyed-Saeed Hashemi-Nazari
Amir Kavousi
Fatemeh Hadavandsiri
Afshin Ostovar
Koorosh Etemad
author_facet Somayeh Derakhshan
Davood Khalili
Alireza Mahdavi
Seyed-Saeed Hashemi-Nazari
Amir Kavousi
Fatemeh Hadavandsiri
Afshin Ostovar
Koorosh Etemad
author_sort Somayeh Derakhshan
collection DOAJ
description Abstract Background To assess the effectiveness of the IraPEN program in decreasing the risk of cardiovascular disease (CVD) and associated risk factors in selected areas of Iran. Methods A secondary data analysis of longitudinal data collected between 2016 and 2017 from health centers in four pilot areas. The target population consisted of people aged 40 years and above, as well as individuals aged 30–40 years who had at least one CVD risk factor. We compared mean CVD risk and risk factor levels before and one year after the intervention and utilized Generalized Estimating Equations to analyze the trends during subsequent visits. Results A total of 160,223 eligible individuals (93,081 female) were screened at baseline, of which 25,764 individuals (17,386 female) were followed up for at least one year. The proportion of men with a CVD risk score above 10%, according to the WHO/ISH risk charts, decreased from 7.5 to 5.3%, while the proportion of women decreased from 6.1 to 4.7%. Based on the revised WHO risk score, the mean CVD risk for those with a risk score above 10% at baseline and one year later was 0.198 and 0.177 in men and 0.119 and 0.109 in women, respectively. There was a significant decrease in all risk factors, except for waist circumference in both sexes and BMI in women. The trend analysis of risk factors over time confirmed these findings. Conclusion The program was modestly effective in reducing CVD risk in the pilot areas. However, further modifications may be needed to enhance its effectiveness.
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spelling doaj-art-809c647fb39f4806ba1ae0aa492b6da52025-02-09T12:57:46ZengBMCBMC Public Health1471-24582025-02-0125111010.1186/s12889-024-21168-3Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areasSomayeh Derakhshan0Davood Khalili1Alireza Mahdavi2Seyed-Saeed Hashemi-Nazari3Amir Kavousi4Fatemeh Hadavandsiri5Afshin Ostovar6Koorosh Etemad7Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical SciencesPrevention of Metabolic Disorders Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesCenter for Noncommunicable Disease Control and Prevention, Ministry of Health (MOH)Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical SciencesDepartment of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical SciencesDepartment of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical SciencesOsteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical SciencesDepartment of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical SciencesAbstract Background To assess the effectiveness of the IraPEN program in decreasing the risk of cardiovascular disease (CVD) and associated risk factors in selected areas of Iran. Methods A secondary data analysis of longitudinal data collected between 2016 and 2017 from health centers in four pilot areas. The target population consisted of people aged 40 years and above, as well as individuals aged 30–40 years who had at least one CVD risk factor. We compared mean CVD risk and risk factor levels before and one year after the intervention and utilized Generalized Estimating Equations to analyze the trends during subsequent visits. Results A total of 160,223 eligible individuals (93,081 female) were screened at baseline, of which 25,764 individuals (17,386 female) were followed up for at least one year. The proportion of men with a CVD risk score above 10%, according to the WHO/ISH risk charts, decreased from 7.5 to 5.3%, while the proportion of women decreased from 6.1 to 4.7%. Based on the revised WHO risk score, the mean CVD risk for those with a risk score above 10% at baseline and one year later was 0.198 and 0.177 in men and 0.119 and 0.109 in women, respectively. There was a significant decrease in all risk factors, except for waist circumference in both sexes and BMI in women. The trend analysis of risk factors over time confirmed these findings. Conclusion The program was modestly effective in reducing CVD risk in the pilot areas. However, further modifications may be needed to enhance its effectiveness.https://doi.org/10.1186/s12889-024-21168-3Cardiovascular diseaseRisk factorsRisk scorePreventionIran
spellingShingle Somayeh Derakhshan
Davood Khalili
Alireza Mahdavi
Seyed-Saeed Hashemi-Nazari
Amir Kavousi
Fatemeh Hadavandsiri
Afshin Ostovar
Koorosh Etemad
Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
BMC Public Health
Cardiovascular disease
Risk factors
Risk score
Prevention
Iran
title Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
title_full Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
title_fullStr Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
title_full_unstemmed Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
title_short Evaluation of the effectiveness of the Iran-package of essential non-communicable disease (IraPEN) program in reducing cardiovascular disease risk in pilot areas
title_sort evaluation of the effectiveness of the iran package of essential non communicable disease irapen program in reducing cardiovascular disease risk in pilot areas
topic Cardiovascular disease
Risk factors
Risk score
Prevention
Iran
url https://doi.org/10.1186/s12889-024-21168-3
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