Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids
A Boc-protocol for manual solid-phase synthesis of novel sequences of negatively charged oligomeric polyamide mimetics of nucleic acids with a regular structure of the pseudopeptide backbone based on L-glutamic acid and glycine and having various positions of the carbethoxyethyl moiety was developed...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
MIREA - Russian Technological University
2011-04-01
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| Series: | Тонкие химические технологии |
| Subjects: | |
| Online Access: | https://www.finechem-mirea.ru/jour/article/view/867 |
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| _version_ | 1849343011590242304 |
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| author | M. V. Shiryaeva Yu. G. Kirillova O. V. Esipova S. V. Eremin T. A. Lukyanova V. I. Shvets |
| author_facet | M. V. Shiryaeva Yu. G. Kirillova O. V. Esipova S. V. Eremin T. A. Lukyanova V. I. Shvets |
| author_sort | M. V. Shiryaeva |
| collection | DOAJ |
| description | A Boc-protocol for manual solid-phase synthesis of novel sequences of negatively charged oligomeric polyamide mimetics of nucleic acids with a regular structure of the pseudopeptide backbone based on L-glutamic acid and glycine and having various positions of the carbethoxyethyl moiety was developed. Conditions for their cleavage from polymeric carrier, isolation and structure confirmation are presented. |
| format | Article |
| id | doaj-art-8098b0fe7d9c4582861714ea994bdae8 |
| institution | Kabale University |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2011-04-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-8098b0fe7d9c4582861714ea994bdae82025-08-20T03:43:11ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752011-04-01628185861Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acidsM. V. Shiryaeva0Yu. G. Kirillova1O. V. Esipova2S. V. Eremin3T. A. Lukyanova4V. I. Shvets5M.V. Lomonosov Moscow University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571ООО «НПФ Литех»M.V. Lomonosov Moscow University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571A Boc-protocol for manual solid-phase synthesis of novel sequences of negatively charged oligomeric polyamide mimetics of nucleic acids with a regular structure of the pseudopeptide backbone based on L-glutamic acid and glycine and having various positions of the carbethoxyethyl moiety was developed. Conditions for their cleavage from polymeric carrier, isolation and structure confirmation are presented.https://www.finechem-mirea.ru/jour/article/view/867peptide nucleic acidspolyamide mimetics of nucleic acidssolid-phase synthesisboc-protocol |
| spellingShingle | M. V. Shiryaeva Yu. G. Kirillova O. V. Esipova S. V. Eremin T. A. Lukyanova V. I. Shvets Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids Тонкие химические технологии peptide nucleic acids polyamide mimetics of nucleic acids solid-phase synthesis boc-protocol |
| title | Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| title_full | Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| title_fullStr | Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| title_full_unstemmed | Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| title_short | Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| title_sort | solid phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids |
| topic | peptide nucleic acids polyamide mimetics of nucleic acids solid-phase synthesis boc-protocol |
| url | https://www.finechem-mirea.ru/jour/article/view/867 |
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