Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet
Two Rapid, direct, ecological friendly and economical spectrophotometric methods were used for estimation of meloxicam in the market Tablet dosage form. The First method is based on the use the fourth order derivative spectrum (D4) and the second method is depend-ed on the ratio of the area under th...
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| Language: | English |
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Mustansiriyah University
2019-03-01
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| Series: | Al-Mustansiriyah Journal of Science |
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| Online Access: | http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/624 |
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| author | Ruba Fahmi Abbas Neda Ibrahim Mahdi Ali Amer Waheb Amer Waheb Amjad Gali Aliwi Gali Aliwi Marwa S. Falih |
| author_facet | Ruba Fahmi Abbas Neda Ibrahim Mahdi Ali Amer Waheb Amer Waheb Amjad Gali Aliwi Gali Aliwi Marwa S. Falih |
| author_sort | Ruba Fahmi Abbas |
| collection | DOAJ |
| description | Two Rapid, direct, ecological friendly and economical spectrophotometric methods were used for estimation of meloxicam in the market Tablet dosage form. The First method is based on the use the fourth order derivative spectrum (D4) and the second method is depend-ed on the ratio of the area under the curve for the two peaks in the drug (Compensated area under the curve). The linear calibration graphs of the two methods were measured in the con-centration range (5-35)mg/l and the average of recoveries for local market Tablet (AWA)® were 99.8% for D4 method and 100.2% for CAUC method which indicating a good accuracy and precision for these methods. In this study, the results obtained by these suggested meth-ods have been successfully statistically compared by t-test and Mann-Whitney test showed a good agreement. |
| format | Article |
| id | doaj-art-80975e0bc1ae44b980cbbd8f19f46656 |
| institution | OA Journals |
| issn | 1814-635X 2521-3520 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Science |
| spelling | doaj-art-80975e0bc1ae44b980cbbd8f19f466562025-08-20T02:22:38ZengMustansiriyah UniversityAl-Mustansiriyah Journal of Science1814-635X2521-35202019-03-01293707610.23851/mjs.v29i3.624199Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market TabletRuba Fahmi Abbas0Neda Ibrahim Mahdi1Ali Amer Waheb Amer Waheb2Amjad Gali Aliwi Gali Aliwi3Marwa S. Falih4Department of Chemistry, Collage of Science, Mustansiriyah University, IRAQ.Department of Chemistry, Collage of Science, Mustansiriyah University, IRAQ.Department of Chemistry, Collage of Science, Mustansiriyah University, IRAQ.Department of Chemistry, Collage of Science, Mustansiriyah University, IRAQ.Department of Chemistry, Collage of Science, Mustansiriyah University, IRAQ.Two Rapid, direct, ecological friendly and economical spectrophotometric methods were used for estimation of meloxicam in the market Tablet dosage form. The First method is based on the use the fourth order derivative spectrum (D4) and the second method is depend-ed on the ratio of the area under the curve for the two peaks in the drug (Compensated area under the curve). The linear calibration graphs of the two methods were measured in the con-centration range (5-35)mg/l and the average of recoveries for local market Tablet (AWA)® were 99.8% for D4 method and 100.2% for CAUC method which indicating a good accuracy and precision for these methods. In this study, the results obtained by these suggested meth-ods have been successfully statistically compared by t-test and Mann-Whitney test showed a good agreement.http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/624meloxicamD4CAUCspectrophotometricMann-Whitney test |
| spellingShingle | Ruba Fahmi Abbas Neda Ibrahim Mahdi Ali Amer Waheb Amer Waheb Amjad Gali Aliwi Gali Aliwi Marwa S. Falih Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet Al-Mustansiriyah Journal of Science meloxicam D4 CAUC spectrophotometric Mann-Whitney test |
| title | Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet |
| title_full | Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet |
| title_fullStr | Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet |
| title_full_unstemmed | Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet |
| title_short | Fourth Derivative and Compensated Area under the Curve Spectrophotometric Methods Used for Analysis Meloxicam in the Local Market Tablet |
| title_sort | fourth derivative and compensated area under the curve spectrophotometric methods used for analysis meloxicam in the local market tablet |
| topic | meloxicam D4 CAUC spectrophotometric Mann-Whitney test |
| url | http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/624 |
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