Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography
Objective. We applied optical flow method (OFM) to quantify relative velocities of blood flow using digital subtraction angiography (DSA) in the vascular analysis of hepatocellular carcinoma (HCC) patients who underwent transarterial chemoembolization (TACE) treatment. Methods. A total of 40 HCC pat...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/830531 |
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| author | Yung-Jen Ho Mu-Bai Chang Yang-Hsien Lin Chun-Hsu Yao Tzung-Chi Huang |
| author_facet | Yung-Jen Ho Mu-Bai Chang Yang-Hsien Lin Chun-Hsu Yao Tzung-Chi Huang |
| author_sort | Yung-Jen Ho |
| collection | DOAJ |
| description | Objective. We applied optical flow method (OFM) to quantify relative velocities of blood flow using digital subtraction angiography (DSA) in the vascular analysis of hepatocellular carcinoma (HCC) patients who underwent transarterial chemoembolization (TACE) treatment. Methods. A total of 40 HCC patients treated by TACE were analyzed in this study. DSA imaging with a 12-inch field of view, 1024 × 1024 pixels and 4 frames/second was acquired. OFM developed for motion estimation is applied for blood flow estimation. Two acrylic phantoms were built to validate the method. Results. The relationship between the OFM and Doppler measurements was found linear with R2=0.99 for both straight and curved tube phantoms. Quantitative blood flow distribution images of the portal vein region were presented. After TACE, the minimum, maximum and mean velocities in the portal vein all decreased (P<0.05). Additionally, the velocity in the portal vein is significantly lower with a higher Child-Pugh score (P<0.01). Conclusions. The present technique provides add-on quantitative information of flows to DSA and the hemodynamic analysis in relative quantifications of blood flow in portal vein of hepatocellular carcinoma patients using DSA. |
| format | Article |
| id | doaj-art-8096fb725d5746f89abbf4b815a46aee |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-8096fb725d5746f89abbf4b815a46aee2025-08-20T03:35:14ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/830531830531Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on AngiographyYung-Jen Ho0Mu-Bai Chang1Yang-Hsien Lin2Chun-Hsu Yao3Tzung-Chi Huang4Department of Biomedical Imaging and Radiological Science, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanDepartment of Biomedical Imaging and Radiological Science, China Medical University, 91 Hsueh-Shih Road, Taichung 404, TaiwanObjective. We applied optical flow method (OFM) to quantify relative velocities of blood flow using digital subtraction angiography (DSA) in the vascular analysis of hepatocellular carcinoma (HCC) patients who underwent transarterial chemoembolization (TACE) treatment. Methods. A total of 40 HCC patients treated by TACE were analyzed in this study. DSA imaging with a 12-inch field of view, 1024 × 1024 pixels and 4 frames/second was acquired. OFM developed for motion estimation is applied for blood flow estimation. Two acrylic phantoms were built to validate the method. Results. The relationship between the OFM and Doppler measurements was found linear with R2=0.99 for both straight and curved tube phantoms. Quantitative blood flow distribution images of the portal vein region were presented. After TACE, the minimum, maximum and mean velocities in the portal vein all decreased (P<0.05). Additionally, the velocity in the portal vein is significantly lower with a higher Child-Pugh score (P<0.01). Conclusions. The present technique provides add-on quantitative information of flows to DSA and the hemodynamic analysis in relative quantifications of blood flow in portal vein of hepatocellular carcinoma patients using DSA.http://dx.doi.org/10.1100/2012/830531 |
| spellingShingle | Yung-Jen Ho Mu-Bai Chang Yang-Hsien Lin Chun-Hsu Yao Tzung-Chi Huang Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography The Scientific World Journal |
| title | Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography |
| title_full | Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography |
| title_fullStr | Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography |
| title_full_unstemmed | Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography |
| title_short | Quantitative Portal Vein Velocity of Liver Cancer Patients with Transcatheter Arterial Chemoembolization on Angiography |
| title_sort | quantitative portal vein velocity of liver cancer patients with transcatheter arterial chemoembolization on angiography |
| url | http://dx.doi.org/10.1100/2012/830531 |
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