Side effects of retinoid therapy on the quality of vision

Retinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous mechanisms of action leading to normalization of keratinocyte proliferation and maturation. They have anti-seborrhoeic, immunomodulatory and anti-infl...

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Main Authors: Bergler-Czop Beata, Bilewicz-Stebel Monika, Stańkowska Anna, Bilewicz-Wyrozumska Teresa
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2016-0039
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author Bergler-Czop Beata
Bilewicz-Stebel Monika
Stańkowska Anna
Bilewicz-Wyrozumska Teresa
author_facet Bergler-Czop Beata
Bilewicz-Stebel Monika
Stańkowska Anna
Bilewicz-Wyrozumska Teresa
author_sort Bergler-Czop Beata
collection DOAJ
description Retinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous mechanisms of action leading to normalization of keratinocyte proliferation and maturation. They have anti-seborrhoeic, immunomodulatory and anti-inflammatory effects (1, 2). A number of side effects to retinoid treatment have been recorded; one group of such side effects relates to eyes and vision. Dry eye syndrome and blepharoconjunctivitis are the most common side effects, appearing in 20-50 % of patients treated with retinoids. They often contribute to the occurrence of other side-effects such as eye discomfort and contact lens intolerance. Due to the widespread use in clinical practice, the adverse effects, including ocular side effects, should be studied. To confirm the variety of adverse effects of retinoids, several case reports of rare side-effects are presented.
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institution Kabale University
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series Acta Pharmaceutica
spelling doaj-art-808aed0fc3774da4964fc2f6c40ee6772025-02-02T15:47:07ZengSciendoActa Pharmaceutica1846-95582016-12-0166447147810.1515/acph-2016-0039acph-2016-0039Side effects of retinoid therapy on the quality of visionBergler-Czop Beata0Bilewicz-Stebel Monika1Stańkowska Anna2Bilewicz-Wyrozumska Teresa3Department of Dermatology, Medical University of Silesia 40-027, Katowice, PolandProvincial Specialized Hospital, MEGREZ Sp. z o. o. 43-100 Tychy, PolandAndrzej Mielęcki Silesian Independent, Public Clinical Hospital in Katowice, Department of Dermatology, 40-027 Katowice, PolandDepartment of Environmental Health, School of Public Health in Bytom, Medical University of Silesia School of Public Health in Bytom, 41-902 Bytom, PolandRetinoids are compounds chemically related to vitamin A, which are frequently used in dermatological practice (1). They are characterized by numerous mechanisms of action leading to normalization of keratinocyte proliferation and maturation. They have anti-seborrhoeic, immunomodulatory and anti-inflammatory effects (1, 2). A number of side effects to retinoid treatment have been recorded; one group of such side effects relates to eyes and vision. Dry eye syndrome and blepharoconjunctivitis are the most common side effects, appearing in 20-50 % of patients treated with retinoids. They often contribute to the occurrence of other side-effects such as eye discomfort and contact lens intolerance. Due to the widespread use in clinical practice, the adverse effects, including ocular side effects, should be studied. To confirm the variety of adverse effects of retinoids, several case reports of rare side-effects are presented.https://doi.org/10.1515/acph-2016-0039retinoidsisotretinoinadverse effectseyesacne
spellingShingle Bergler-Czop Beata
Bilewicz-Stebel Monika
Stańkowska Anna
Bilewicz-Wyrozumska Teresa
Side effects of retinoid therapy on the quality of vision
Acta Pharmaceutica
retinoids
isotretinoin
adverse effects
eyes
acne
title Side effects of retinoid therapy on the quality of vision
title_full Side effects of retinoid therapy on the quality of vision
title_fullStr Side effects of retinoid therapy on the quality of vision
title_full_unstemmed Side effects of retinoid therapy on the quality of vision
title_short Side effects of retinoid therapy on the quality of vision
title_sort side effects of retinoid therapy on the quality of vision
topic retinoids
isotretinoin
adverse effects
eyes
acne
url https://doi.org/10.1515/acph-2016-0039
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AT bilewiczstebelmonika sideeffectsofretinoidtherapyonthequalityofvision
AT stankowskaanna sideeffectsofretinoidtherapyonthequalityofvision
AT bilewiczwyrozumskateresa sideeffectsofretinoidtherapyonthequalityofvision