Machine learning assisted adjustment boosts efficiency of exact inference in randomized controlled trials

Abstract In this work, we proposed a novel inferential procedure assisted by machine learning based adjustment for randomized control trials. The method was developed under the Rosenbaum’s framework of exact tests in randomized experiments with covariate adjustments, replacing the traditional linear...

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Bibliographic Details
Main Authors: Han Yu, Alan Hutson, Xiaoyi Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-10566-1
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