Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021
Abstract Background Estimation of global diabetes burden in adolescents and young adults (10–24 years) from 1990 to 2021. Methods Data were extracted from the 2021 Global Burden of Disease Study. Joinpoint regression analysis was employed to examine trends over the past 30 years, frontier analysis i...
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BMC
2024-10-01
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| Series: | Diabetology & Metabolic Syndrome |
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| Online Access: | https://doi.org/10.1186/s13098-024-01491-w |
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| author | Yan Liu Shenhang Yao Xiangxiang Shan Yuting Luo Lulu Yang Wu Dai Ben Hu |
| author_facet | Yan Liu Shenhang Yao Xiangxiang Shan Yuting Luo Lulu Yang Wu Dai Ben Hu |
| author_sort | Yan Liu |
| collection | DOAJ |
| description | Abstract Background Estimation of global diabetes burden in adolescents and young adults (10–24 years) from 1990 to 2021. Methods Data were extracted from the 2021 Global Burden of Disease Study. Joinpoint regression analysis was employed to examine trends over the past 30 years, frontier analysis identified regions with potential for improvement, and the slope index of inequality and the relative concentration index were used to assess health inequalities. Results From 1990 to 2021, the age-standardized prevalence rates (ASPR) and age-standardized disability-adjusted life years rates (ASDR) of diabetes in adolescents and young adults increased globally, while age-standardized death rates (ASMR) remained stable. Oceania bore the highest burden regionally, East Asia experienced the fastest rise in ASPR and ASDR, and High-income Asia Pacific saw the most significant decrease in ASMR. Among 204 countries, Marshall Island and Hait reported the highest ASPR, ASDR, and ASMR in 2021. Health inequality analysis confirmed that the burden was concentrated in countries with lower Socio-Demographic Index (SDI). Frontier analysis showed that ASMR and ASDR were negatively correlated with SDI, with Yemen and Honduras, which have lower socio-demographic indices, exhibiting more smaller overall differences from frontier boundaries. Conclusions The analysis revealed a sharp increase in the global ASPR and ASDR of diabetes in adolescents and young adults. Additionally, the disease burden is typically concentrated in countries with lower SDI, highlighting an urgent need for governments to develop flexible health policies to mitigate the escalating threat of diabetes in this demographic. |
| format | Article |
| id | doaj-art-8077648a6b3d47b29ecfe320d65ee9e0 |
| institution | OA Journals |
| issn | 1758-5996 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | BMC |
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| series | Diabetology & Metabolic Syndrome |
| spelling | doaj-art-8077648a6b3d47b29ecfe320d65ee9e02025-08-20T02:11:22ZengBMCDiabetology & Metabolic Syndrome1758-59962024-10-0116111210.1186/s13098-024-01491-wTime trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021Yan Liu0Shenhang Yao1Xiangxiang Shan2Yuting Luo3Lulu Yang4Wu Dai5Ben Hu6Department of Endocrinology, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical UniversityDepartment of Endocrinology, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical UniversityDepartment of Endocrinology, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical UniversityDepartment of Science and Education, The Second People’s Hospital of Hefei, Hefei Hospital, Affiliated to Anhui Medical UniversityDepartment of Science and Education, The Second People’s Hospital of Hefei, Hefei Hospital, Affiliated to Anhui Medical UniversityDepartment of Endocrinology, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical UniversityDepartment of Cardiology, The Second People’s Hospital of Hefei, Hefei Hospital, Affiliated to Anhui Medical UniversityAbstract Background Estimation of global diabetes burden in adolescents and young adults (10–24 years) from 1990 to 2021. Methods Data were extracted from the 2021 Global Burden of Disease Study. Joinpoint regression analysis was employed to examine trends over the past 30 years, frontier analysis identified regions with potential for improvement, and the slope index of inequality and the relative concentration index were used to assess health inequalities. Results From 1990 to 2021, the age-standardized prevalence rates (ASPR) and age-standardized disability-adjusted life years rates (ASDR) of diabetes in adolescents and young adults increased globally, while age-standardized death rates (ASMR) remained stable. Oceania bore the highest burden regionally, East Asia experienced the fastest rise in ASPR and ASDR, and High-income Asia Pacific saw the most significant decrease in ASMR. Among 204 countries, Marshall Island and Hait reported the highest ASPR, ASDR, and ASMR in 2021. Health inequality analysis confirmed that the burden was concentrated in countries with lower Socio-Demographic Index (SDI). Frontier analysis showed that ASMR and ASDR were negatively correlated with SDI, with Yemen and Honduras, which have lower socio-demographic indices, exhibiting more smaller overall differences from frontier boundaries. Conclusions The analysis revealed a sharp increase in the global ASPR and ASDR of diabetes in adolescents and young adults. Additionally, the disease burden is typically concentrated in countries with lower SDI, highlighting an urgent need for governments to develop flexible health policies to mitigate the escalating threat of diabetes in this demographic.https://doi.org/10.1186/s13098-024-01491-wDiabetesAdolescents and young adultsGlobal burden of disease 2021Joinpoint regression analysisEpidemiology |
| spellingShingle | Yan Liu Shenhang Yao Xiangxiang Shan Yuting Luo Lulu Yang Wu Dai Ben Hu Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 Diabetology & Metabolic Syndrome Diabetes Adolescents and young adults Global burden of disease 2021 Joinpoint regression analysis Epidemiology |
| title | Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 |
| title_full | Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 |
| title_fullStr | Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 |
| title_full_unstemmed | Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 |
| title_short | Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10–24 years, 1990–2021: analysis for the global burden of disease study 2021 |
| title_sort | time trends and advances in the management of global regional and national diabetes in adolescents and young adults aged 10 24 years 1990 2021 analysis for the global burden of disease study 2021 |
| topic | Diabetes Adolescents and young adults Global burden of disease 2021 Joinpoint regression analysis Epidemiology |
| url | https://doi.org/10.1186/s13098-024-01491-w |
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