Treatment of acute bipolar depression
Depression is the predominant pole of disability in bipolar disorder and compared with mania/hypomania, has less systematic research guiding the development of treatment especially in its acute phase (acute bipolar depression). The deficiency in the management of the acute bipolar depression largely...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2018-01-01
|
| Series: | Tzu Chi Medical Journal |
| Subjects: | |
| Online Access: | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=141;epage=147;aulast=Shen |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850215438221312000 |
|---|---|
| author | Yu-Chih Shen |
| author_facet | Yu-Chih Shen |
| author_sort | Yu-Chih Shen |
| collection | DOAJ |
| description | Depression is the predominant pole of disability in bipolar disorder and compared with mania/hypomania, has less systematic research guiding the development of treatment especially in its acute phase (acute bipolar depression). The deficiency in the management of the acute bipolar depression largely reflects the natural divergence of opinion resulting from significant knowledge gaps. At present, there are only 3 approved drug treatments for acute bipolar depression: olanzapine/fluoxetine combination, quetiapine (immediate or extended release), and lurasidone (monotherapy or adjunctive to lithium or valproate). Nonapproved agents and nonpharmacologic treatment such as lamotrigine, antidepressants, modafinil, pramipexole, ketamine, and electroconvulsive therapy are often prescribed to treat acute bipolar depression. This article discusses the challenges of diagnosing bipolar depression, and reviews above treatment options for acute bipolar depression. |
| format | Article |
| id | doaj-art-806c6801de7445fda534a2e8a8d99e8c |
| institution | OA Journals |
| issn | 1016-3190 2223-8956 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tzu Chi Medical Journal |
| spelling | doaj-art-806c6801de7445fda534a2e8a8d99e8c2025-08-20T02:08:36ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562018-01-0130314114710.4103/tcmj.tcmj_71_18Treatment of acute bipolar depressionYu-Chih ShenDepression is the predominant pole of disability in bipolar disorder and compared with mania/hypomania, has less systematic research guiding the development of treatment especially in its acute phase (acute bipolar depression). The deficiency in the management of the acute bipolar depression largely reflects the natural divergence of opinion resulting from significant knowledge gaps. At present, there are only 3 approved drug treatments for acute bipolar depression: olanzapine/fluoxetine combination, quetiapine (immediate or extended release), and lurasidone (monotherapy or adjunctive to lithium or valproate). Nonapproved agents and nonpharmacologic treatment such as lamotrigine, antidepressants, modafinil, pramipexole, ketamine, and electroconvulsive therapy are often prescribed to treat acute bipolar depression. This article discusses the challenges of diagnosing bipolar depression, and reviews above treatment options for acute bipolar depression.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=141;epage=147;aulast=ShenAcute bipolar depressionLurasidoneOlanzapine/fluoxetine combinationQuetiapine |
| spellingShingle | Yu-Chih Shen Treatment of acute bipolar depression Tzu Chi Medical Journal Acute bipolar depression Lurasidone Olanzapine/fluoxetine combination Quetiapine |
| title | Treatment of acute bipolar depression |
| title_full | Treatment of acute bipolar depression |
| title_fullStr | Treatment of acute bipolar depression |
| title_full_unstemmed | Treatment of acute bipolar depression |
| title_short | Treatment of acute bipolar depression |
| title_sort | treatment of acute bipolar depression |
| topic | Acute bipolar depression Lurasidone Olanzapine/fluoxetine combination Quetiapine |
| url | http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2018;volume=30;issue=3;spage=141;epage=147;aulast=Shen |
| work_keys_str_mv | AT yuchihshen treatmentofacutebipolardepression |