Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea

Fungi are the prominent phytopathogens that have significant impact on the productivity of agriculture worldwide. Streptomyces species have been extensively studied for the production of various bioactive metabolites. These metabolites have been used as biocontrol agents for the management of diseas...

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Main Authors: DaYoung Kim, Jungyeon Kim, Younmi Lee, Kotnala Balaraju, Ye-Ji Hwang, Mi-Hwa Lee, Wonsu Cheon, Hye Yeon Mun, Chang Soo Lee, Yongho Jeon
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1429646/full
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author DaYoung Kim
Jungyeon Kim
Younmi Lee
Kotnala Balaraju
Ye-Ji Hwang
Mi-Hwa Lee
Wonsu Cheon
Hye Yeon Mun
Chang Soo Lee
Yongho Jeon
author_facet DaYoung Kim
Jungyeon Kim
Younmi Lee
Kotnala Balaraju
Ye-Ji Hwang
Mi-Hwa Lee
Wonsu Cheon
Hye Yeon Mun
Chang Soo Lee
Yongho Jeon
author_sort DaYoung Kim
collection DOAJ
description Fungi are the prominent phytopathogens that have significant impact on the productivity of agriculture worldwide. Streptomyces species have been extensively studied for the production of various bioactive metabolites. These metabolites have been used as biocontrol agents for the management of diseases caused by phytopathogenic fungi. The purpose of this investigation is to assess the efficacy of Streptomyces sporoverrucosus B-1662, an antagonistic agent in the control of red pepper anthracnose caused by Colletotrichum acutatum KACC 42403 and apple anthracnose caused by Colletotrichum siamense CGCP6 (GYUN-10348). On the basis of the morphological, and molecular characterization using 16S rRNA, the strain B-1662 was determined to be S. sporoverrucosus. The strain B-1662 exhibited antagonistic activity against seven fungal phytopathogens, including C. acutatum KACC 42403 and C. siamense CGCP6. The culture filtrates (CF) from B-1662 showed antifungal activity against all seven fungal pathogens with greater inhibition rate (%) in comparison with a control. The bacterial suspensions of B-1662 showed an excellent biological control effect on the red pepper anthracnose and apple bitter rot using an in planta assay. The anthracnose disease rate (%) was controlled by over 90% with B-1662 cell suspensions at 105 to 107 CFU/mL. Compared to a control, the strain B-1662 played a more effective role in controlling the anthracnose disease in field conditions in both years 2022 and 2023. From the effective solvent fractions, the effect compound (dibutoxybutane) has been isolated exhibiting with antifungal effect. The genetic base underlying the biocontrol traits of B-1662 was characterized using the whole-genome sequence of B-1662, which was compared with closely related strains. Consequently, these results collectively suggest that S. sporoverrucosus B-1662 can aid in the management of red-pepper anthracnose.
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spelling doaj-art-805e4d4b62e649f8b3f7270858fb06f02025-08-20T01:54:15ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2024-11-011510.3389/fmicb.2024.14296461429646Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in KoreaDaYoung Kim0Jungyeon Kim1Younmi Lee2Kotnala Balaraju3Ye-Ji Hwang4Mi-Hwa Lee5Wonsu Cheon6Hye Yeon Mun7Chang Soo Lee8Yongho Jeon9Department of Plant Medicals, Andong National University, Andong, Republic of KoreaDepartment of Plant Medicals, Andong National University, Andong, Republic of KoreaDepartment of Plant Medicals, Andong National University, Andong, Republic of KoreaAgricultural Science and Technology Research Institute, Andong National University, Andong, Republic of KoreaUsing Technology Development Department, Sangju, Republic of KoreaDiversity Conservation Research Department, Sangju, Republic of KoreaBiological Resources Research Department, Nakdonggang National Institute of Biological Resources, Sangju, Republic of KoreaBiological Resources Research Department, Nakdonggang National Institute of Biological Resources, Sangju, Republic of KoreaBiological Resources Research Department, Nakdonggang National Institute of Biological Resources, Sangju, Republic of KoreaDepartment of Plant Medicals, Andong National University, Andong, Republic of KoreaFungi are the prominent phytopathogens that have significant impact on the productivity of agriculture worldwide. Streptomyces species have been extensively studied for the production of various bioactive metabolites. These metabolites have been used as biocontrol agents for the management of diseases caused by phytopathogenic fungi. The purpose of this investigation is to assess the efficacy of Streptomyces sporoverrucosus B-1662, an antagonistic agent in the control of red pepper anthracnose caused by Colletotrichum acutatum KACC 42403 and apple anthracnose caused by Colletotrichum siamense CGCP6 (GYUN-10348). On the basis of the morphological, and molecular characterization using 16S rRNA, the strain B-1662 was determined to be S. sporoverrucosus. The strain B-1662 exhibited antagonistic activity against seven fungal phytopathogens, including C. acutatum KACC 42403 and C. siamense CGCP6. The culture filtrates (CF) from B-1662 showed antifungal activity against all seven fungal pathogens with greater inhibition rate (%) in comparison with a control. The bacterial suspensions of B-1662 showed an excellent biological control effect on the red pepper anthracnose and apple bitter rot using an in planta assay. The anthracnose disease rate (%) was controlled by over 90% with B-1662 cell suspensions at 105 to 107 CFU/mL. Compared to a control, the strain B-1662 played a more effective role in controlling the anthracnose disease in field conditions in both years 2022 and 2023. From the effective solvent fractions, the effect compound (dibutoxybutane) has been isolated exhibiting with antifungal effect. The genetic base underlying the biocontrol traits of B-1662 was characterized using the whole-genome sequence of B-1662, which was compared with closely related strains. Consequently, these results collectively suggest that S. sporoverrucosus B-1662 can aid in the management of red-pepper anthracnose.https://www.frontiersin.org/articles/10.3389/fmicb.2024.1429646/fullapplebiocontrol agentColletotrichum diseasepepperStreptomyces sporoverrucosus B-1662whole-genome sequencing
spellingShingle DaYoung Kim
Jungyeon Kim
Younmi Lee
Kotnala Balaraju
Ye-Ji Hwang
Mi-Hwa Lee
Wonsu Cheon
Hye Yeon Mun
Chang Soo Lee
Yongho Jeon
Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
Frontiers in Microbiology
apple
biocontrol agent
Colletotrichum disease
pepper
Streptomyces sporoverrucosus B-1662
whole-genome sequencing
title Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
title_full Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
title_fullStr Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
title_full_unstemmed Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
title_short Evaluation of Streptomyces sporoverrucosus B-1662 for biological control of red pepper anthracnose and apple bitter rot diseases in Korea
title_sort evaluation of streptomyces sporoverrucosus b 1662 for biological control of red pepper anthracnose and apple bitter rot diseases in korea
topic apple
biocontrol agent
Colletotrichum disease
pepper
Streptomyces sporoverrucosus B-1662
whole-genome sequencing
url https://www.frontiersin.org/articles/10.3389/fmicb.2024.1429646/full
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