The Ubx Polycomb response element bypasses an unpaired Fab-8 insulator via cis transvection in Drosophila.

The Ubx Polycomb response element bypasses an unpaired Fab-8 insulator via cis transvection in Drosophila.

Chromatin insulators or boundary elements protect genes from regulatory activities from neighboring genes or chromatin domains. In the Drosophila Abdominal-B (Abd-B) locus, the deletion of such elements, such as Frontabdominal-7 (Fab-7) or Fab-8 led to dominant gain of function phenotypes, presumabl...

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Main Authors: Danfeng Lu, Zhuoran Li, Lingling Li, Liping Yang, Guijun Chen, Deying Yang, Yue Zhang, Vikrant Singh, Sheryl Smith, Yu Xiao, Erlin Wang, Yunshuang Ye, Wei Zhang, Lei Zhou, Yikang Rong, Jumin Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0199353&type=printable
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