Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation

Diffeomorphic demons can guarantee smooth and reversible deformation and avoid unreasonable deformation. However, the number of iterations needs to be set manually, and this greatly influences the registration result. In order to solve this problem, we proposed adaptive diffeomorphic multiresolution...

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Main Authors: Chang Wang, Qiongqiong Ren, Xin Qin, Yi Yu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2018/7314612
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author Chang Wang
Qiongqiong Ren
Xin Qin
Yi Yu
author_facet Chang Wang
Qiongqiong Ren
Xin Qin
Yi Yu
author_sort Chang Wang
collection DOAJ
description Diffeomorphic demons can guarantee smooth and reversible deformation and avoid unreasonable deformation. However, the number of iterations needs to be set manually, and this greatly influences the registration result. In order to solve this problem, we proposed adaptive diffeomorphic multiresolution demons in this paper. We used an optimized framework with nonrigid registration and diffeomorphism strategy, designed a similarity energy function based on grey value, and stopped iterations adaptively. This method was tested by synthetic image and same modality medical image. Large deformation was simulated by rotational distortion and extrusion transform, medical image registration with large deformation was performed, and quantitative analyses were conducted using the registration evaluation indexes, and the influence of different driving forces and parameters on the registration result was analyzed. The registration results of same modality medical images were compared with those obtained using active demons, additive demons, and diffeomorphic demons. Quantitative analyses showed that the proposed method’s normalized cross-correlation coefficient and structural similarity were the highest and mean square error was the lowest. Medical image registration with large deformation could be performed successfully; evaluation indexes remained stable with an increase in deformation strength. The proposed method is effective and robust, and it can be applied to nonrigid registration of same modality medical images with large deformation.
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institution Kabale University
issn 1687-4188
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spelling doaj-art-8042cf8e7f47447591aec8a7357caf172025-08-20T03:35:14ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962018-01-01201810.1155/2018/73146127314612Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large DeformationChang Wang0Qiongqiong Ren1Xin Qin2Yi Yu3School of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, ChinaSchool of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, ChinaSchool of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, ChinaSchool of Biomedical Engineering, Xinxiang Medical University, Xinxiang 453003, ChinaDiffeomorphic demons can guarantee smooth and reversible deformation and avoid unreasonable deformation. However, the number of iterations needs to be set manually, and this greatly influences the registration result. In order to solve this problem, we proposed adaptive diffeomorphic multiresolution demons in this paper. We used an optimized framework with nonrigid registration and diffeomorphism strategy, designed a similarity energy function based on grey value, and stopped iterations adaptively. This method was tested by synthetic image and same modality medical image. Large deformation was simulated by rotational distortion and extrusion transform, medical image registration with large deformation was performed, and quantitative analyses were conducted using the registration evaluation indexes, and the influence of different driving forces and parameters on the registration result was analyzed. The registration results of same modality medical images were compared with those obtained using active demons, additive demons, and diffeomorphic demons. Quantitative analyses showed that the proposed method’s normalized cross-correlation coefficient and structural similarity were the highest and mean square error was the lowest. Medical image registration with large deformation could be performed successfully; evaluation indexes remained stable with an increase in deformation strength. The proposed method is effective and robust, and it can be applied to nonrigid registration of same modality medical images with large deformation.http://dx.doi.org/10.1155/2018/7314612
spellingShingle Chang Wang
Qiongqiong Ren
Xin Qin
Yi Yu
Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
International Journal of Biomedical Imaging
title Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
title_full Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
title_fullStr Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
title_full_unstemmed Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
title_short Adaptive Diffeomorphic Multiresolution Demons and Their Application to Same Modality Medical Image Registration with Large Deformation
title_sort adaptive diffeomorphic multiresolution demons and their application to same modality medical image registration with large deformation
url http://dx.doi.org/10.1155/2018/7314612
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AT qiongqiongren adaptivediffeomorphicmultiresolutiondemonsandtheirapplicationtosamemodalitymedicalimageregistrationwithlargedeformation
AT xinqin adaptivediffeomorphicmultiresolutiondemonsandtheirapplicationtosamemodalitymedicalimageregistrationwithlargedeformation
AT yiyu adaptivediffeomorphicmultiresolutiondemonsandtheirapplicationtosamemodalitymedicalimageregistrationwithlargedeformation