Evolutionary View of Liver Pathology

ABSTRACT Evolutionary medicine emerged in the late twentieth century, integrating principles of natural selection and adaptation with the health sciences. Today, with a rapidly widening gap between the biology of Homo sapiens and its environment, maladaptation or maladaptive disorders can be detecte...

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Main Authors: Katalin Dezső, Sándor Paku, Mária‐Manuela Juhász, László Kóbori, Péter Nagy
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Evolutionary Applications
Subjects:
Online Access:https://doi.org/10.1111/eva.70059
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author Katalin Dezső
Sándor Paku
Mária‐Manuela Juhász
László Kóbori
Péter Nagy
author_facet Katalin Dezső
Sándor Paku
Mária‐Manuela Juhász
László Kóbori
Péter Nagy
author_sort Katalin Dezső
collection DOAJ
description ABSTRACT Evolutionary medicine emerged in the late twentieth century, integrating principles of natural selection and adaptation with the health sciences. Today, with a rapidly widening gap between the biology of Homo sapiens and its environment, maladaptation or maladaptive disorders can be detected in almost all diseases, including liver dysfunction. However, in hepatology, as in most medical specialties, evolutionary considerations are neglected because the majority of the medical community is not familiar with evolutionary principles. The aim of this brief review is to highlight an evolutionary approach that may facilitate understanding various liver diseases.
format Article
id doaj-art-8040421fb8d64b4c8cd1e585ae5baedb
institution Kabale University
issn 1752-4571
language English
publishDate 2024-12-01
publisher Wiley
record_format Article
series Evolutionary Applications
spelling doaj-art-8040421fb8d64b4c8cd1e585ae5baedb2025-01-29T07:57:46ZengWileyEvolutionary Applications1752-45712024-12-011712n/an/a10.1111/eva.70059Evolutionary View of Liver PathologyKatalin Dezső0Sándor Paku1Mária‐Manuela Juhász2László Kóbori3Péter Nagy4Department of Pathology and Experimental Cancer Research Semmelweis University Budapest HungaryDepartment of Pathology and Experimental Cancer Research Semmelweis University Budapest HungaryDepartment of Pathology and Experimental Cancer Research Semmelweis University Budapest HungaryDepartment of Surgery, Transplantation and Gastroenterology Semmelweis University Budapest HungaryDepartment of Pathology and Experimental Cancer Research Semmelweis University Budapest HungaryABSTRACT Evolutionary medicine emerged in the late twentieth century, integrating principles of natural selection and adaptation with the health sciences. Today, with a rapidly widening gap between the biology of Homo sapiens and its environment, maladaptation or maladaptive disorders can be detected in almost all diseases, including liver dysfunction. However, in hepatology, as in most medical specialties, evolutionary considerations are neglected because the majority of the medical community is not familiar with evolutionary principles. The aim of this brief review is to highlight an evolutionary approach that may facilitate understanding various liver diseases.https://doi.org/10.1111/eva.70059evolutionhepatitishepatocarcinogenesis
spellingShingle Katalin Dezső
Sándor Paku
Mária‐Manuela Juhász
László Kóbori
Péter Nagy
Evolutionary View of Liver Pathology
Evolutionary Applications
evolution
hepatitis
hepatocarcinogenesis
title Evolutionary View of Liver Pathology
title_full Evolutionary View of Liver Pathology
title_fullStr Evolutionary View of Liver Pathology
title_full_unstemmed Evolutionary View of Liver Pathology
title_short Evolutionary View of Liver Pathology
title_sort evolutionary view of liver pathology
topic evolution
hepatitis
hepatocarcinogenesis
url https://doi.org/10.1111/eva.70059
work_keys_str_mv AT katalindezso evolutionaryviewofliverpathology
AT sandorpaku evolutionaryviewofliverpathology
AT mariamanuelajuhasz evolutionaryviewofliverpathology
AT laszlokobori evolutionaryviewofliverpathology
AT peternagy evolutionaryviewofliverpathology