Immunoglobulin E (IgE)-mediated food allergy

Abstract Food allergy is defined as an adverse immunologic response to a food. Immunoglobulin E (IgE)-mediated reactions to foods are associated with a broad range of signs and symptoms that may involve any of the following body systems: the skin, gastrointestinal tract, respiratory tract, and cardi...

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Main Authors: Philippe Bégin, Susan Waserman, Jennifer L. P. Protudjer, Samira Jeimy, Wade Watson
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:https://doi.org/10.1186/s13223-024-00930-7
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author Philippe Bégin
Susan Waserman
Jennifer L. P. Protudjer
Samira Jeimy
Wade Watson
author_facet Philippe Bégin
Susan Waserman
Jennifer L. P. Protudjer
Samira Jeimy
Wade Watson
author_sort Philippe Bégin
collection DOAJ
description Abstract Food allergy is defined as an adverse immunologic response to a food. Immunoglobulin E (IgE)-mediated reactions to foods are associated with a broad range of signs and symptoms that may involve any of the following body systems: the skin, gastrointestinal tract, respiratory tract, and cardiovascular system. IgE-mediated food allergy is a leading cause of anaphylaxis. Therefore, timely and appropriate diagnosis and treatment are imperative. A diagnosis of food allergy entails a careful history and diagnostic tests, which may include skin prick tests, serum-specific IgE, and oral food challenge. The goal of food allergy care is to empower patients and caregivers to manage the risk of food-allergic reactions, reduce food allergy-related anxiety, and achieve a sense of control over their condition. This can be achieved in different ways for different patients and across different life stages. This article provides an overview of the epidemiology, pathophysiology, diagnosis, and management of IgE-mediated food allergy.
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series Allergy, Asthma & Clinical Immunology
spelling doaj-art-803d52c1900d437ea4fa74939c2b7fec2025-01-05T12:33:23ZengBMCAllergy, Asthma & Clinical Immunology1710-14922024-12-0120S311310.1186/s13223-024-00930-7Immunoglobulin E (IgE)-mediated food allergyPhilippe Bégin0Susan Waserman1Jennifer L. P. Protudjer2Samira Jeimy3Wade Watson4Division of Clinical Immunology and Allergy, Department of Medicine, Université de MontréalDivision of Clinical Immunology and Allergy, Department of Medicine, McMaster UniversityDepartment of Pediatrics and Child Health, College of Medicine, Rady Faculty of Health Sciences, University of ManitobaDivision of Clinical Immunology and Allergy, Department of Medicine, Western UniversityDivision of Allergy, Department of Pediatrics, Dalhousie University, IWK Health CentreAbstract Food allergy is defined as an adverse immunologic response to a food. Immunoglobulin E (IgE)-mediated reactions to foods are associated with a broad range of signs and symptoms that may involve any of the following body systems: the skin, gastrointestinal tract, respiratory tract, and cardiovascular system. IgE-mediated food allergy is a leading cause of anaphylaxis. Therefore, timely and appropriate diagnosis and treatment are imperative. A diagnosis of food allergy entails a careful history and diagnostic tests, which may include skin prick tests, serum-specific IgE, and oral food challenge. The goal of food allergy care is to empower patients and caregivers to manage the risk of food-allergic reactions, reduce food allergy-related anxiety, and achieve a sense of control over their condition. This can be achieved in different ways for different patients and across different life stages. This article provides an overview of the epidemiology, pathophysiology, diagnosis, and management of IgE-mediated food allergy.https://doi.org/10.1186/s13223-024-00930-7
spellingShingle Philippe Bégin
Susan Waserman
Jennifer L. P. Protudjer
Samira Jeimy
Wade Watson
Immunoglobulin E (IgE)-mediated food allergy
Allergy, Asthma & Clinical Immunology
title Immunoglobulin E (IgE)-mediated food allergy
title_full Immunoglobulin E (IgE)-mediated food allergy
title_fullStr Immunoglobulin E (IgE)-mediated food allergy
title_full_unstemmed Immunoglobulin E (IgE)-mediated food allergy
title_short Immunoglobulin E (IgE)-mediated food allergy
title_sort immunoglobulin e ige mediated food allergy
url https://doi.org/10.1186/s13223-024-00930-7
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AT susanwaserman immunoglobulineigemediatedfoodallergy
AT jenniferlpprotudjer immunoglobulineigemediatedfoodallergy
AT samirajeimy immunoglobulineigemediatedfoodallergy
AT wadewatson immunoglobulineigemediatedfoodallergy