INTERACTION OF DOXORUBICIN WITH
DNA-HMG1 COMPLEX

INTERACTION OF DOXORUBICIN WITH DNA-HMG1 COMPLEX

In this study, the interaction of the anthracycline antibiotic doxorubicin with DNA-HMG 1 complex was investigated employing UV/VIS spectroscopy, thermal denaturation and DNA cellulose chromatography techniques. The results indicated that the binding of doxorubicin to the protein reduces its Tm in a...

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Bibliographic Details
Format:	Article
Language:	English
Published:	University of Tehran 1995-08-01
Series:	Journal of Sciences, Islamic Republic of Iran
Online Access:	https://jsciences.ut.ac.ir/article_31334_d8baabdbd0ee99b0d7fa5b84008f7955.pdf
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