Enhanced healing of critical-sized bone defects using degradable scaffolds with tailored composition through immunomodulation and angiogenesis

Enhanced healing of critical-sized bone defects using degradable scaffolds with tailored composition through immunomodulation and angiogenesis

The impact of orthopedic scaffolds on bone defect healing, particularly the late-stage bone remodeling process, is pivotal for the therapeutic outcome. This study applies fadditively manufactured scaffolds composed of hydroxyapatite-doped poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lac...

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Bibliographic Details
Main Authors: Juncen Zhou, Negar Akrami, Hanbo Wang, Liang Fang, Jie Shen, Cunjiang Yu, Ben Zhang, Donghui Zhu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-02-01
Series:Bioactive Materials
Subjects:
Additive manufacturing
Polymer scaffolds
Biodegradable
Bone defect healing
Bone remodeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004638
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