Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study

Background: Rheumatoid arthritis (RA) is an autoimmune disorder affecting the joints, causing inflammation and potential structural damage. While conventional radiography often reveals damage only in later stages, ultrasonography (USG) offers a dynamic, noninvasive imaging option with greater patien...

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Main Authors: Alka Agrawal, Prachi Shukla, Hema Dhakad, Mona, Mayank Patidar, Manzill
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:APIK Journal of Internal Medicine
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Online Access:https://journals.lww.com/10.4103/ajim.ajim_83_24
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author Alka Agrawal
Prachi Shukla
Hema Dhakad
Mona
Mayank Patidar
Manzill
author_facet Alka Agrawal
Prachi Shukla
Hema Dhakad
Mona
Mayank Patidar
Manzill
author_sort Alka Agrawal
collection DOAJ
description Background: Rheumatoid arthritis (RA) is an autoimmune disorder affecting the joints, causing inflammation and potential structural damage. While conventional radiography often reveals damage only in later stages, ultrasonography (USG) offers a dynamic, noninvasive imaging option with greater patient acceptability. Materials and Methods: A cross-sectional study was conducted at a medical college hospital in India, involving 50 clinically diagnosed RA patients. US (7–13 MHz) was used to assess wrist and hand joints for synovial hypertrophy, vascularity using power Doppler (PD), bone erosions, and joint effusion. Results: Among patients aged 20–80 years, the mean age was 54 years, the median age was 49.5 years with an interquartile range of 11.5 years, and 84% were female. US detected synovial thickening in 80% of wrist joints and 68% of hand joints, with bone erosions found in 42% of wrist and 36% of hand joints. PD detected increased vascularity in 60% of cases. X-rays revealed soft-tissue swelling in 16% of wrist and 8% of hand joints, with bone erosions in 24% of wrist joints. US showed higher sensitivity (83.3% for wrist and 87.5% for hand) and specificity (68.4% for wrist and 71.4% for hand) in detecting bone erosions compared to X-ray. Conclusion: Grayscale USG and PD are valuable tools for assessing joint abnormalities in patients with RA. Their ability to detect synovial changes and vascular activity supports accurate disease evaluation and aids in treatment planning, particularly in hand and wrist joints.
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spelling doaj-art-802e8b78a94f48b0ae2c730fc17cd5602025-08-20T02:42:36ZengWolters Kluwer Medknow PublicationsAPIK Journal of Internal Medicine2666-18022666-18102025-07-0113318318810.4103/ajim.ajim_83_24Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional StudyAlka AgrawalPrachi ShuklaHema DhakadMonaMayank PatidarManzillBackground: Rheumatoid arthritis (RA) is an autoimmune disorder affecting the joints, causing inflammation and potential structural damage. While conventional radiography often reveals damage only in later stages, ultrasonography (USG) offers a dynamic, noninvasive imaging option with greater patient acceptability. Materials and Methods: A cross-sectional study was conducted at a medical college hospital in India, involving 50 clinically diagnosed RA patients. US (7–13 MHz) was used to assess wrist and hand joints for synovial hypertrophy, vascularity using power Doppler (PD), bone erosions, and joint effusion. Results: Among patients aged 20–80 years, the mean age was 54 years, the median age was 49.5 years with an interquartile range of 11.5 years, and 84% were female. US detected synovial thickening in 80% of wrist joints and 68% of hand joints, with bone erosions found in 42% of wrist and 36% of hand joints. PD detected increased vascularity in 60% of cases. X-rays revealed soft-tissue swelling in 16% of wrist and 8% of hand joints, with bone erosions in 24% of wrist joints. US showed higher sensitivity (83.3% for wrist and 87.5% for hand) and specificity (68.4% for wrist and 71.4% for hand) in detecting bone erosions compared to X-ray. Conclusion: Grayscale USG and PD are valuable tools for assessing joint abnormalities in patients with RA. Their ability to detect synovial changes and vascular activity supports accurate disease evaluation and aids in treatment planning, particularly in hand and wrist joints.https://journals.lww.com/10.4103/ajim.ajim_83_24bone erosionsdisease activitypower dopplerrheumatoid arthritissynovial hypertrophyultrasonography
spellingShingle Alka Agrawal
Prachi Shukla
Hema Dhakad
Mona
Mayank Patidar
Manzill
Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
APIK Journal of Internal Medicine
bone erosions
disease activity
power doppler
rheumatoid arthritis
synovial hypertrophy
ultrasonography
title Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
title_full Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
title_fullStr Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
title_full_unstemmed Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
title_short Ultrasonographic Detection of Joint Abnormalities in Rheumatoid Arthritis: A Cross-sectional Study
title_sort ultrasonographic detection of joint abnormalities in rheumatoid arthritis a cross sectional study
topic bone erosions
disease activity
power doppler
rheumatoid arthritis
synovial hypertrophy
ultrasonography
url https://journals.lww.com/10.4103/ajim.ajim_83_24
work_keys_str_mv AT alkaagrawal ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy
AT prachishukla ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy
AT hemadhakad ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy
AT mona ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy
AT mayankpatidar ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy
AT manzill ultrasonographicdetectionofjointabnormalitiesinrheumatoidarthritisacrosssectionalstudy