DDX1 is required for non-spliceosomal splicing of tRNAs but not of XBP1 mRNA
Abstract RNA helicase DEAD-box helicase 1 (DDX1) forms a complex with the RNA ligase 2´,3´-cyclic phosphate and 5´-OH ligase (RTCB), which plays a vital role in non-spliceosomal splicing of tRNA and X-box binding protein 1 (XBP1) mRNA. However, the importance of DDX1 in non-spliceosomal splicing has...
Saved in:
Main Authors: | Teruhiko Suzuki, Satoko Takagi, Junta Funada, Yuka Egawa, Mana Yamakawa, Takahiko Hara |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-025-07523-z |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs
by: Kejia Zhang, et al.
Published: (2025-01-01) -
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction
by: Hongjian Zhou, et al.
Published: (2025-01-01) -
Correction: DDX43 mRNA expression and protein levels in relation to clinicopathological profile of breast cancer.
by: Noha N Amer, et al.
Published: (2024-01-01) -
Substrate Specificities of DDX1: A Human DEAD-Box Protein
by: Anthony F. T. Moore, et al.
Published: (2025-01-01) -
Maternal phthalates exposure promotes neural stem cell differentiation into phagocytic astrocytes and synapse engulfment via IRE1α/XBP1s pathway
by: Fengzhen Cui, et al.
Published: (2025-01-01)