Association of high-density lipoprotein cholesterol with reduced intracranial haemorrhage and favourable functional outcome after thrombectomy for ischaemic stroke: a propensity-matched analysis

Association of high-density lipoprotein cholesterol with reduced intracranial haemorrhage and favourable functional outcome after thrombectomy for ischaemic stroke: a propensity-matched analysis

Abstract Background Animal studies suggest that high-density lipoprotein cholesterol (HDL-C) attenuates reperfusion injury. We aimed to assess whether higher serum HDL-C levels modulate the risk of intracranial haemorrhage (ICH) after thrombectomy in human stroke survivors. Methods We included conse...

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Bibliographic Details
Main Authors: Annahita Sedghi, Sonja Schreckenbauer, Daniel P. O. Kaiser, Ani Cuberi, Witold H. Polanski, Martin Arndt, Kristian Barlinn, Volker Puetz, Timo Siepmann
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Neurological Research and Practice
Subjects:
Ischaemic stroke
High density lipoprotein
Endovascular therapy
Thrombectomy
Reperfusion injury
Bleeding
Online Access:https://doi.org/10.1186/s42466-025-00373-4
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